SCO0348 protein (Streptomyces coelicolor) - STRING interaction network
"SCO0348" - SCF41.07, possible 2-hydroxyacid-family dehydrogenase, len: 339 aa. Similar to Mycobacterium leprae SW:SERA_MYCLE (EMBL in Streptomyces coelicolor
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Known Interactions
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Predicted Interactions
gene neighborhood
gene fusions
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Gene Fusion
SCO0348SCF41.07, possible 2-hydroxyacid-family dehydrogenase, len- 339 aa. Similar to Mycobacterium leprae SW-SERA_MYCLE (EMBL; Z99263) D-3-phosphoglycerate dehydrogenase (EC (PGDH) MLCB637.25 (528 aa), fasta scores opt- 452 z-score- 525.4 E()- 6.5e-22 36.7% identity in 286 aa overlap and Pyrococcus abyssi TR-CAB49675 (EMBL; AJ248285) SERA-like protein (307 aa), fasta scores opt- 437 z-score- 511.6 E()- 3.8e-21 32.0% identity in 309 aa overlap. Contains a Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases (339 aa)    
Predicted Functional Partners:
SCF41.08, possible oxidoreductase (hypothetical protein), len- 334 aa. Similar to Pseudomonas sp. TR-Q52472 (EMBL; D32042) L-fucose dehydrogenase (329 aa), fasta scores opt- 960 z-score- 1078.8 E()- 0 48.4% identity in 318 aa overlap (334 aa)
SCF41.06, possible racemase, len- 416 aa. Similar to Pseudomonas putida SW-MANR_PSEPU (EMBL; M19043) mandelate racemase (EC (359 aa), fasta scores opt- 322 z-score- 326.6 E()- 7.7e-11 27.9% identity in 366 aa overlap. Contains a Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family. This gene is duplicated on this cosmid and shares 74.3% identity, in 378 aa overlap, with the downstream gene, SCF41.17. Note the predicted protein product of SCF41.06 is 36 aa longer than that of SCF41.17 (416 aa)
Uncharacterized protein; SCF41.10, unknown, len- 491 aa (491 aa)
Uncharacterized protein; SCF41.09, unknown, len- 334 aa. Similar to several hypotheticals including- Rhizobium sp. SW-Y4MH_RHISN (EMBL; AE000085) hypothetical 33.9 KD protein Y4MH (297 aa), fasta scores opt- 262 z-score- 309.5 E()- 6.9e-10 23.8% identity in 303 aa overlap (294 aa)
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily (363 aa)
SCF41.13, possible binding-protein-dependent transport protein, len- 280 aa, Similar to many e.g. Streptomyces coelicolor TR-O50501 (EMBL; AL009199) probable transmembrane transport protein SC7b7.04 (302 aa), fasta scores opt- 584 z-score- 670.3 E()- 5.5e-30 36.1% identity in 274 aa overlap. Contains multiple membrane spanning hydrophobic domains, a PS00402 Binding-protein-dependent transport systems inner membrane comp sign and a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component (280 aa)
SCF41.12, possible binding-protein-dependent transport protein, len- 303 aa. Similar to many including- Streptomyces coelicolor TR-CAB41203 (EMBL; AL049661) binding protein dependent transport protein SCE134.05c (327 aa), fasta scores opt- 560 z-score- 661.2 E()- 1.8e-29 35.5% identity in 301 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains multiple potential membrane-spanning hydrophobic domains (303 aa)
SCF41.11 possible solute-binding protein, len- 422 aa. Similar to many including- Streptomyces lividans TR-Q9Z492 (EMBL; AF043654) BxlE precursor (434 aa), fasta scores opt- 287 z-score- 311.3 E()- 5.5e-10 25.7% identity in 354 aa overlap. Contains a PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a possible N-terminal signal sequence (422 aa)
SCC57A.23c, possible oxidoreductase, len- 378 aa. Weakly similar to several other oxidoreductases e.g. Streptomyces coelicolor TR-O69945 (EMBL-AL023862) oxidoreductase (430 aa), fasta scores opt- 252 z-score- 300.4 E()- 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family (378 aa)
SCC57A.21c, hypothetical protein, len- 287 aa; similar to TR-CAC41509 (EMBL-AL591782) Rhizobium meliloti (Sinorhizobium meliloti) conserved hypothetical protein SMC04130, 274 aa; fasta scores- opt- 796 Z-score- 889.6 E()- 6.4e-42; 47.191% identity in 267 aa overlap (287 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor, Streptomyces coelicolor A3(2)
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