STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO0575Putative peptidase; Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids. (243 aa)    
Predicted Functional Partners:
SCO0574
SC5G5.06, probable IclR-family regulatory protein, len: 277 aa; similar to SW:ICLR_ECOLI (EMBL:M31761) Escherichia coli acetate operon repressor IclR or B4018, 274 aa; fasta scores: opt: 281 Z-score: 332.8 bits: 69.4 E(): 6.1e-11; 25.926% identity in 243 aa overlap and to SW:GYLR_STRCO (EMBL:X14188) Streptomyces coelicolor glycerol operon regulatory protein GylR or SCI46.03, 254 aa; fasta scores: opt: 290 Z-score: 343.7 bits: 71.3 E(): 1.5e-11; 30.588% identity in 255 aa overlap. Contains Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator.
 
     0.847
SCO0573
SC5G5.05c, conserved hypothetical protein, len: 317 aa; similar to TR:O58746 (EMBL:AP000004) Pyrococcus horikoshii hypothetical 34.0 kDa protein PH1050, 315 aa; fasta scores: opt: 1322 Z-score: 1394.2 bits: 266.2 E(): 4.6e-70; 61.981% identity in 313 aa overlap.
 
     0.831
SCO0571
SC5G5.03c, possible peptidase, len: 442 aa; similar to TR:Q9CC46 (EMBL:AL583921) Mycobacterium leprae possible peptidase ML1288, 467 aa; fasta scores: opt: 1502 Z-score: 1703.4 bits: 324.4 E(): 2.7e-87; 52.874% identity in 435 aa overlap and to TR:CAC36379 (EMBL:AL590507) Streptomyces coelicolor putative peptidase SCI52.18c, 445 aa; fasta scores: opt: 1590 Z-score: 1803.4 bits: 342.9 E(): 7.5e-93; 56.706% identity in 425 aa overlap. Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40 and match to Prosite entry PS00758 ArgE / dapE.
     
 0.584
SCO0572
SC5G5.04c, probable cytosine permease, len: 466 aa; similar to SW:CODB_ECOLI (EMBL:X63656) Escherichia coli cytosine permease CodB or B0336, 419 aa; fasta scores: opt: 509 Z-score: 543.6 bits: 109.7 E(): 1.1e-22; 27.427% identity in 412 aa overlap. Contains Pfam match to entry PF02133 Transp_cyt_pur, Permease for cytosine/purines, uracil, thiamine, allantoin and possible hydrophobic membrane spanning regions.
       0.582
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.