STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1173SCG11A.04, possible transcriptional regulator, len: aa; similar to TR:O31551 (EMBL:Z99108) Bacillus subtilis transcriptional regulator AcoR, 605 aa; fasta scores: opt: 393 z-score: 446.5 E(): 1.7e-17; 34.7% identity in 199 aa overlap. (419 aa)    
Predicted Functional Partners:
SCO1192
SCG11A.23, hypothetical protein, len:122 aa; similar to various hypothetical proteins, e.g. TR:O53744 (EMBL:AL021933) Mycobacterium tuberculosis hypothetical 17.2 KD protein MTV038.03, 163 aa; fasta scores: opt: 478 z-score: 600.7 E(): 4.4e-26; 66.7% identity in 111 aa overlap.
 
     0.832
SCO1174
SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site.
 
 
 
 0.817
SCO1170
Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
       0.632
SCO0580
SCF55.04c, possible glycerone kinase, len: 593 aa; similar to SW:DHAK_YEAST (EMBL:D50617) Saccharomyces cerevisiae dihydroxyacetone kinase 2 (EC 2.7.1.29) (glycerone kinase) Dak2, 591 aa; fasta scores: opt: 646 z-score: 660.2 E(): 2.1e-29; 29.9% identity in 561 aa overlap.
   
 
 0.629
SCO7072
SC4G1.38c, hypothetical protein, len: 199 aa; similar to SW:YCGS_ECOLI (EMBL:AE000218) Escherichia coli hypothetical 22.6 kDa protein in TreA-Pth intergenic region YcgS, 210 aa; fasta scores: opt: 349 z-score: 387.3 E(): 4.2e-14; 44.5% identity in 200 aa overlap and to C-terminal region of SW:DAK1_YEAST (EMBL:Z38114) Saccharomyces cerevisiae dihydroxyacetone kinase 1 (EC 2.7.1.29) Dak1, 584 aa; fasta scores: opt: 298 z-score: 326.4 E(): 1e-10; 33.3% identity in 189 aa overlap.
   
 
 0.629
SCO7073
SC4G1.39c, hypothetical protein, len: 330 aa; similar to SW:YCGT_ECOLI (EMBL:AE000218) Escherichia coli hypothetical 39.5 kDa protein in TreA-Pth intergenic region YcgT, 366 aa; fasta scores: opt: 876 z-score: 955.5 E(): 0; 46.2% identity in 355 aa overlap, to N-terminal region of SW:DAK1_YEAST (EMBL:Z38114) Saccharomyces cerevisiae dihydroxyacetone kinase 1 (EC 2.7.1.29) Dak1, 584 aa; fasta scores: opt: 516 z-score: 562.8 E(): 7e-24; 34.0% identity in 312 aa overlap and to TR:AAK84068 (EMBL:AF297121) Selenomonas ruminantium subsp. ruminantium dihydroxyacetone kinase DhaK1, 329 aa; fas [...]
   
 
 0.629
SCO1169
2SCG11.03c, xylA, xylose isomerase, len: 387 aa; identical to SW:XYLA_STRRU (EMBL:M73789) Streptomyces rubiginosus xylose isomerase XylA, 387 aa. Contains Pfam match to entry PF00259 Xylose_isom, Xylose isomerase and matches to Prosite entries PS00172 Xylose isomerase signature 1 and PS00173 Xylose isomerase signature 2.
       0.557
SCO1172
SCG11A.03, probable amidase (putative secreted protein), len: 201 aa; similar to SW:AMPD_ECOLI (EMBL:X15237) Escherichia coli anhydro-N-acetylmuramyl-tripeptide amidase AmpD, 183aa; fasta scores: opt: 211 z-score: 267.1 E(): 1.7e-07; 39.5% identity in 114 aa overlap and to Streptomyces coelicolor SC2A11.21c; fasta scores: opt: 674 z-score: 751.6 E(): 0; 50.0% identity in 202 aa overlap. Contains match to Pfam entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase. Contains possible N-terminal region signal peptide sequence.
       0.552
SCO2747
SCC57A.18, bifunctional carbohydrate binding and transport protein, len: 613 aa. The N-terminus is highly similar to many ribose transport system permeases e.g. Escherichia coli SW:RBSC_ECOLI(EMBL:L10328) ribose transport system permease protein RbsC (321 aa), fasta scores opt: 846 z-score: 833.8 E(): 0 47.1% identity in 310 aa overlap. The C-terminus is highly similar to many ribose-binding proteins e.g. Escherichia coli SW:RBSB_ECOLI(EMBL:K00511) D-ribose-binding periplasmic protein precursor (296 aa), fasta scores opt: 863 z-score: 847.0 E():0 46.9% identity in 303 aa overlap. Conta [...]
   
    0.524
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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