STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1917Conserved hypothetical protein; SCI7.35c, unknown, len: 197aa; similar to many eg. TR:P95092 (EMBL:Z83866) hypothetical protein from Mycobacterium tuberculosis (202 aa) fasta scores; opt: 398, z-score: 482.3, E(): 1.6e-19, (40.3% identity in 191 aa overlap). (197 aa)    
Predicted Functional Partners:
SCO1918
SCI7.36c, possible integral membrane protein, len: 106aa; similar to many proposed to be involved in resistance mechanisms eg. SW:EMRE_ECOLI viologen resistance protein from Escherichia coli (110 aa) fasta scores; opt: 313, z-score: 392.7, E(): 1.5e-14, (51.0% identity in 100 aa overlap). Contains Pfam match to entry PF00893 DUF7, Integral membrane protein.
  
    0.876
SCO1916
Putative transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
       0.875
SCO1919
SCC22.01c, partial CDS, conserved hypothetical protein, len: >75aa; similar to many other hypothetical proteins eg. TR:O53157 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (115 aa) fasta scores; opt: 284, z-score: 392.0, E(): 1.7e-14, (61.3% identity in 80 aa overlap); SCI7.37c, partial CDS, unknown, len: >74aa; similar to TR:O53157 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (115 aa) fasta scores; opt: 375, z-score: 536.1, E(): 1.6e-22, (70.1% identity in 77 aa overlap).
       0.772
SCO1920
SCC22.02c, conserved hypothetical protein, len: 156aa; similar to many other hypothetical protein eg. TR:O53156 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (162 aa) fasta scores; opt: 569, z-score: 685.8, E(): 7.2e-31, (56.3% identity in 158 aa overlap) and to SW:NIFU_BACSU (EMBL:Z99120) Bacillus subtilis NifU-like protein NifU, 147 aa; fasta scores: opt: 439 Z-score: 527.7 E(): 9.3e-22; 45.517% identity in 145 aa overlap.
       0.772
SCO1921
Putative aminotransferase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
       0.762
SCO1922
SCC22.04c, possible ABC transporter ATP-binding subunit, len: 254aa; similar to many proposed ABC transporter subunit eg. SW:ABCX_CYAPA probable ATP-dependent transporter from Cyanophora paradoxa (259 aa) fasta scores; opt: 856, z-score: 945.3, E(): 0, (55.3% identity in 246 aa overlap). Also highly similar to TR:O53154 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (266 aa) fasta scores; opt: 1258, z-score: 1383.7, E(): 0, (76.9% identity in 251 aa overlap). Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and Prosite match to PS00017 ATP/GTP-bindin [...]
       0.762
SCO1923
SCC22.05c, possible dioxygenase ferredoxin subunit, len: 105 aa; similar to many e.g. SW:BEDB_PSEPU benzene dioxygenase from Pseudomonas putida ML2 (107 aa) fasta scores; opt: 286, z-score: 390.9, E(): 1.9e-14, (40.6% identity in 101 aa overlap).
       0.762
SCO1924
SCC22.06c, conserved hypothetical protein, len: 394aa; similar to many eg. TR:O53153 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (397 aa) fasta scores; opt: 1446, z-score: 1649.9, E(): 0, (58.0% identity in 388 aa overlap). Contains Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051).
       0.762
SCO1926
SCC22.08c, possible DNA-binding protein, len: 252aa; similar to TR:O53151 (EMBL:AL021184) hypothetical protein from Mycobacterium tuberculosis (278 aa) fasta scores; opt: 629, z-score: 705.6, E(): 5.8e-32, (46.8% identity in 233 aa overlap). Contains a helix-turn-helix motif (+4.75 SD) at residues 34-55.
  
    0.744
SCO1925
SCC22.07c, conserved hypothetical protein, len: 473aa; similar to many eg. TR:O32162 (EMBL:Z99120) hypothetical protein from Bacillus subtilis (465 aa) fasta scores; opt: 2087, z-score: 2451.5, E(): 0, (64.6% identity in 463 aa overlap). Also similar to the N-terminal region and the C-terminal region of TR:O53152 (EMBL:AL021184) hypothetical splice protein from Mycobacterium tuberculosis (846 aa) fasta scores; opt: 1367, z-score: 1602.5, E(): 0, (47.5% identity in 832 aa overlap). Contains Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051).
       0.717
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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