STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1989Putative aminopeptidase; Specifically catalyzes the removal of N-terminal proline residues from peptides. (323 aa)    
Predicted Functional Partners:
SCO6293
SCBAC8D1.06, conserved hypothetical protein, len: 333 aa; similar to TR:Q9I489 (EMBL:AE004555) Pseudomonas aeruginosa hypothetical protein PA1255, 344 aa; fasta scores: opt: 872 Z-score: 981.3 bits: 190.0 E(): 4.5e-47; 41.964% identity in 336 aa overlap and to TR:Q98F20 (EMBL:AP003003) Rhizobium loti proline racemase MLL3979, 333 aa; fasta scores: opt: 985 Z-score: 1108.1 E(): 4.4e-54; 46.951% identity in 328 aa overlap.
     
 0.925
SCO3337
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
  0.903
SCO5519
Conserved hypothetical protein; SC8D9.31, unknown, len: 308aa; similar to proteins of undefined function eg. TR:O50444 (EMBL:AL010186) from Mycobacterium tuberculosis (329 aa) fasta scores; opt: 984, z-score: 1121.1, E(): 0, (50.0% identity in 312 aa overlap).
     
  0.900
SCO7095
SC3A4.21c, possible hydrolase. len: 318 aa. Similar in parts to several e.g. Moraxella sp. SW:DEH1_MORSP(EMBL:D90422) haloacetate dehalogenase H-1 (EC 3.8.1.3) (294 aa), fasta scores opt: 245 z-score: 286.4 E(): 1.7e-08 37.4% identity in 131 aa overlap. Contains a Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold.
     
  0.900
SCO1990
Conserved hypothetical protein; SC7H2.04c, unknown, len: 237aa; similar to SW:Y08N_MYCTU hypothetical protein from Mycobacterium tuberculosis (350 aa) fasta scores; opt: 870, z-score: 990.4, E(): 0, (57.1% identity in 231 aa overlap).
       0.811
SCO1991
SC7H2.05, hypothetical protein, len: 186 aa; similar to SW:YRFH_ECOLI hypothetical protein from Escherichia coli (133 aa) fasta scores; opt: 228, z-score: 249.5, E(): 1.4e-06, (35.2% identity in 122 aa overlap).
       0.740
SCO6472
SC9C7.08c, meaA, coenzyme B12-dependent mutase, len: 675aa; similar to many, very similar to TR:O33614 (EMBL:AF008569) coenzyme B12-dependent mutase from Streptomyces collinus (674 aa) fasta scores; opt: 4085, z-score: 5046.6, E(): 0, (91.7% identity in 675 aa overlap).
      
 0.612
SCO0883
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      
 0.483
SCO1211
Putative polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      
 0.483
SCO4560
Putative polypetide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
      
 0.483
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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