node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1594 | SCO2465 | gene:17759187 | gene:17760067 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.434 |
SCO1594 | SCO2468 | gene:17759187 | gene:17760070 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.833 |
SCO1594 | SCO2470 | gene:17759187 | gene:17760072 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | SC7A8.09c, probable deoxyguanosine triphosphate triphosphohydrolase, len: 424 aa; similar to TR:O52199 (EMBL:AF027507) Mycobacterium smegmatis dDGTPase Dgt, 428 aa; fasta scores: opt: 1272 z-score: 1453.2 E(): 0; 51.9% identity in 430 aa overlap and similar to N-terminus of SW:DGTP_ECOLI (EMBL:M31772) Escherichia coli deoxyguanosine triphosphate triphosphohydrolase Dgt, 504 aa; fasta scores: opt: 128 z-score: 147.9 E(): 0.76; 34.1% identity in 255 aa overlap; Belongs to the dGTPase family. Type 2 subfamily. | 0.488 |
SCO1594 | SCO2966 | gene:17759187 | gene:17760578 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | Small protein B homologue; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.807 |
SCO1594 | SCO3911 | gene:17759187 | gene:17761538 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | Putative replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.596 |
SCO1594 | SCO4655 | gene:17759187 | gene:17762304 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.920 |
SCO1594 | SCO5624 | gene:17759187 | gene:17763282 | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | SC2E1.41, rpsB, 30S ribosomal protein S2, len: 310 aa; almost identical to RS2_STRCO 30S ribosomal protein S2 (242 aa), E(): 0, 96.7% identity in 242 aa overlap and also highly similar to many others e.g. RS2_ECOLI 30S ribosomal protein S2 (240 aa), fasta scores; opt: 744 z-score: 950.7 E(): 0, 50.4% identity in 224 aa overlap. Contains PS00962 Ribosomal protein S2 signature 1 and PS00211 ABC transporters family signature (probably a false positive). Also contains Pfam matches to entry S2 PF00318, Ribosomal protein S2, score 304.89 and to entry 60s_ribosomal PF00428, 60s Acidic ribosom [...] | 0.978 |
SCO2465 | SCO1594 | gene:17760067 | gene:17759187 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | 0.434 |
SCO2465 | SCO2468 | gene:17760067 | gene:17760070 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.890 |
SCO2465 | SCO2470 | gene:17760067 | gene:17760072 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SC7A8.09c, probable deoxyguanosine triphosphate triphosphohydrolase, len: 424 aa; similar to TR:O52199 (EMBL:AF027507) Mycobacterium smegmatis dDGTPase Dgt, 428 aa; fasta scores: opt: 1272 z-score: 1453.2 E(): 0; 51.9% identity in 430 aa overlap and similar to N-terminus of SW:DGTP_ECOLI (EMBL:M31772) Escherichia coli deoxyguanosine triphosphate triphosphohydrolase Dgt, 504 aa; fasta scores: opt: 128 z-score: 147.9 E(): 0.76; 34.1% identity in 255 aa overlap; Belongs to the dGTPase family. Type 2 subfamily. | 0.560 |
SCO2465 | SCO2966 | gene:17760067 | gene:17760578 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Small protein B homologue; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.511 |
SCO2465 | SCO3911 | gene:17760067 | gene:17761538 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Putative replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.540 |
SCO2465 | SCO4655 | gene:17760067 | gene:17762304 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.961 |
SCO2465 | SCO5624 | gene:17760067 | gene:17763282 | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SC2E1.41, rpsB, 30S ribosomal protein S2, len: 310 aa; almost identical to RS2_STRCO 30S ribosomal protein S2 (242 aa), E(): 0, 96.7% identity in 242 aa overlap and also highly similar to many others e.g. RS2_ECOLI 30S ribosomal protein S2 (240 aa), fasta scores; opt: 744 z-score: 950.7 E(): 0, 50.4% identity in 224 aa overlap. Contains PS00962 Ribosomal protein S2 signature 1 and PS00211 ABC transporters family signature (probably a false positive). Also contains Pfam matches to entry S2 PF00318, Ribosomal protein S2, score 304.89 and to entry 60s_ribosomal PF00428, 60s Acidic ribosom [...] | 0.468 |
SCO2468 | SCO1594 | gene:17760070 | gene:17759187 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | SCI35.16c, pheT, proabable phenylalanyl-tRNA synthetase beta chain, len: 840 aa; similar to many e.g. SYFB_ECOLI phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (795 aa), fasta scores; opt: 988 z-score: 1290.9 E(): 0, 36.0% identity in 849 aa overlap. Contains PS00017 ATP/GTP-binding. | 0.833 |
SCO2468 | SCO2465 | gene:17760070 | gene:17760067 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | RNA polymerase principal sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.890 |
SCO2468 | SCO2470 | gene:17760070 | gene:17760072 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | SC7A8.09c, probable deoxyguanosine triphosphate triphosphohydrolase, len: 424 aa; similar to TR:O52199 (EMBL:AF027507) Mycobacterium smegmatis dDGTPase Dgt, 428 aa; fasta scores: opt: 1272 z-score: 1453.2 E(): 0; 51.9% identity in 430 aa overlap and similar to N-terminus of SW:DGTP_ECOLI (EMBL:M31772) Escherichia coli deoxyguanosine triphosphate triphosphohydrolase Dgt, 504 aa; fasta scores: opt: 128 z-score: 147.9 E(): 0.76; 34.1% identity in 255 aa overlap; Belongs to the dGTPase family. Type 2 subfamily. | 0.896 |
SCO2468 | SCO2904 | gene:17760070 | gene:17760515 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Putative ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.874 |
SCO2468 | SCO2966 | gene:17760070 | gene:17760578 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Small protein B homologue; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] | 0.835 |
SCO2468 | SCO3528 | gene:17760070 | gene:17761149 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Conserved hypothetical protein; SCE2.09, unknown, len: 386 aa; weak similarity to several predicted helicases e.g. SW:DNAB_TREPA replicative DNA helicase from Treponema pallidum (438 aa) fasta scores; opt: 188, z-score: 190.6, E(): 0.0027, (36.5% identity in 156 aa overlap) and similar to TR:Q9L1W8 (EMBL:AL138667) Streptomyces coelicolor hypothetical protein SC3D9.11c, 372 aa; fasta scores: opt: 559 Z-score: 528.6 E(): 8.2e-22; 37.466% identity in 363 aa overlap. | 0.857 |