STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SCO3149Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (286 aa)    
Predicted Functional Partners:
SCO3148
Putative isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
 
  
 0.995
SCO3150
Hypothetical protein; SCE87.01c, unknown, partial CDS, len: > 329 aa. Similar in parts to Mycobacterium tuberculosis TR:O05594 (EMBL:Z94752) hypothetical 38.1 KD protein (362 aa), fasta scores opt: 365 z-score: 372.3 E(): 2.3e-13 34.1% identity in 232 aa overlap and Bacillus subtilis SW:YABE_BACSU (EMBL:D26185) hypothetical 47.7 KD protein (437 aa), fasta scores opt: 315 z-score: 321.5 E(): 1.5e-10 29.2% identity in 233 aa overlap; SCE66.29c, unknown, partial CDS, len: >165aa; similar to TR:O05594 (EMBL:Z94752) hypothetical protein from Mycobacterium tuberculosis (362 aa) fasta scores; [...]
  
  
 0.984
SCO4735
SC6G4.13, rpsI, 30S ribosomal protein S9, len: 170 a a; identical to RS9_STRCO 30S ribosomal protein S9 (170 aa) and highly similar to many e.g.RS9_ECOLI (129 aa), fasta s cores; opt: 408 z-score: 663.5 E(): 1.1e-29, 49.2% identity in 124 aa overlap. Contains PS00360 Ribosomal protein S9 s ignature and Pfam match to entry PF00380 S9, Ribosomal prot ein S9, score 162.60, E-value 1e-49; Belongs to the universal ribosomal protein uS9 family.
 
 
 
 0.931
SCO1505
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.929
SCO4719
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
 
 
 0.925
SCO4659
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS12 family.
   
 
 0.920
SCO3151
SCE87.02c, unknown, len: 296 aa. Highly similar to many hypothetical proteins including: Mycobacterium tuberculosis TR:O08343 (EMBL: Z94752) hypothetical protein YcfH (264 aa), fasta scores opt: 576 z-score: 667.6 E(): 8.2e-30 42.7% identity in 279 aa overlap and Escherichia coli SW:YCFH_ECOLI (EMBL:AE000210) hypothetical 29.8 KD protein (265 aa), fasta scores opt: 477 z-score: 554.2 E(): 1.7e-23 37.0% identity in 276 aa overlap. Contains a Pfam match to entry PF01026 UPF0006, Uncharacterized protein family.
 
  
 0.918
SCO4728
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.917
SCO4660
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.913
SCO4701
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.912
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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