node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0140 | SCO1478 | gene:17757724 | gene:17759064 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.901 |
SCO0140 | SCO4654 | gene:17757724 | gene:17762303 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.918 |
SCO0140 | SCO4655 | gene:17757724 | gene:17762304 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.901 |
SCO0140 | SCO4729 | gene:17757724 | gene:17762378 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.902 |
SCO0140 | SCO5820 | gene:17757724 | gene:17763480 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | Major vegetative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Its activity is stimulated by RbpA. | 0.875 |
SCO1421 | SCO1478 | gene:17759007 | gene:17759064 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.992 |
SCO1421 | SCO4232 | gene:17759007 | gene:17761876 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | SCD8A.05, probable transcriptional factor regulator, len: 160 aa; similar to TR:O53568 (EMBL:AL022075) Mycobacterium tuberculosis putative transcriptional regulator RV3583c, 162 aa; fasta scores: opt: 878 z-score: 1046.7 E(): 0; 85.0% identity in 160 aa overlap. | 0.973 |
SCO1421 | SCO4654 | gene:17759007 | gene:17762303 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.987 |
SCO1421 | SCO4655 | gene:17759007 | gene:17762304 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.985 |
SCO1421 | SCO4729 | gene:17759007 | gene:17762378 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.944 |
SCO1421 | SCO5820 | gene:17759007 | gene:17763480 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | Major vegetative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. Its activity is stimulated by RbpA. | 0.927 |
SCO1478 | SCO0140 | gene:17759064 | gene:17757724 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | 0.901 |
SCO1478 | SCO1421 | gene:17759064 | gene:17759007 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | 0.992 |
SCO1478 | SCO2508 | gene:17759064 | gene:17760110 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | SCC121.11, probable metal uptake regulation protein, len: 139 aa; similar to TR:O05839 (EMBL:Z95208) Mycobacterium tuberculosis cosmid Y27 Fur, 130 aa; fasta scores: opt: 546 z-score: 663.0 E(): 1.5e-29; 61.8% identity in 123 aa overlap and to SW:FUR_NEIGO (EMBL:L11361) Neisseria gonorrhoeae ferric uptake regulation protein (ferric uptake regulator) Fur, 144 aa; fasta scores: opt: 273 z-score: 339.0 E(): 1.7e-11; 35.5% identity in 110 aa overlap. Contains Pfam match to entry PF01475 FUR; Belongs to the Fur family. | 0.806 |
SCO1478 | SCO4223 | gene:17759064 | gene:17761867 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 2SCD46.37c, possible AraC-family transcriptional regulator, len: 295aa; similar to many eg. SW:P22539 (SOXS_ECOLI) regulatory protein SoxS from Escherichia coli (106 aa) fasta scores; opt: 186, z-score: 223.7, E(): 5.4e-05, 28.4% identity in 95 aa overlap and TR:P96662 (EMBL:AB001488) probable hth_arac_family of transcriptional regulator from Bacillus subtilis (290 aa) fasta scores; opt: 726, z-score: 825.6, E(): 0, 37.7% identity in 289 aa overlap. Contains Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family and Prosite match to PS00041 Ba [...] | 0.892 |
SCO1478 | SCO4232 | gene:17759064 | gene:17761876 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | SCD8A.05, probable transcriptional factor regulator, len: 160 aa; similar to TR:O53568 (EMBL:AL022075) Mycobacterium tuberculosis putative transcriptional regulator RV3583c, 162 aa; fasta scores: opt: 878 z-score: 1046.7 E(): 0; 85.0% identity in 160 aa overlap. | 0.953 |
SCO1478 | SCO4443 | gene:17759064 | gene:17762088 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | SCD6.21c, possible merR-family transcriptional regulator, len: 294 aa; similar to TR:AAF11989 (EMBL:AE002074) Deinococcus radiodurans transcriptional regulator, merR-family DR2448, 280 aa; fasta scores: opt: 465 z-score: 562.4 E(): 7.3e-24; 43.0% identity in 286 aa overlap. Contains Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family and match to Prosite entry PS00552 Bacterial regulatory proteins, merR family signature. | 0.901 |
SCO1478 | SCO4654 | gene:17759064 | gene:17762303 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
SCO1478 | SCO4655 | gene:17759064 | gene:17762304 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
SCO1478 | SCO4729 | gene:17759064 | gene:17762378 | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |