STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO6568SC3F9.03, ABC transporter integral membrane protein, len: 339 aa; similar to many involved in sugar transport e.g. RBSC_BACSU ribose transport system permease protein (323 aa), fasta scores; opt: 700 z-score: 958.9 E(): 0, 39.5%identity in 314 aa overlap. (339 aa)    
Predicted Functional Partners:
SCO6567
SC3F9.02, ABC transporter ATP binding protein, len:505 aa; similar to many sugar transport proteins e.g. ARAG_ECOLI l-arabinose transport atp-binding protein (504 aa), fasta scores; opt: 1312 z-score: 1412.8 E(): 0, 42.1% identity in 501 aa overlap andRBSA_HAEIN ribose transport atp-binding protein rbsA (493 aa), fasta scores; opt: 1160 z-score: 1216.7 E(): 0, 40.7% identity in 489 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature and Pfam match to entry ABC_tran PF00005, ABC transporters, score 197.70.
 0.996
SCO6569
SC3F9.04, probable secreted solute binding protein, len: 348 aa; similar to many e.g. RBSB_HAEIN D-ribose-binding periplasmic protein precursor (292 aa), fasta scores; opt: 341 z-score: 284.7 E(): 1.2e-08, 29.2% identity in 271 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
 
 0.996
SCO2746
ABC transporter protein, ATP binding component; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 0.984
SCO2747
SCC57A.18, bifunctional carbohydrate binding and transport protein, len: 613 aa. The N-terminus is highly similar to many ribose transport system permeases e.g. Escherichia coli SW:RBSC_ECOLI(EMBL:L10328) ribose transport system permease protein RbsC (321 aa), fasta scores opt: 846 z-score: 833.8 E(): 0 47.1% identity in 310 aa overlap. The C-terminus is highly similar to many ribose-binding proteins e.g. Escherichia coli SW:RBSB_ECOLI(EMBL:K00511) D-ribose-binding periplasmic protein precursor (296 aa), fasta scores opt: 863 z-score: 847.0 E():0 46.9% identity in 303 aa overlap. Conta [...]
 
0.963
SCO0811
Putative ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
 0.923
SCO2749
Carbohydrate transport protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
  
 0.922
SCO2405
SC4A7.24, probable sugar-transport ATP binding protein, len: 513 aa; similar to TR:AAD45713 (EMBL:AF160811) Bacillus stearothermophilus L-arabinose transport, ATP binding protein AraG, 513 aa; fasta scores: opt: 2220 z-score: 2417.4 E(): 0; 65.5% identity in 510 aa overlap and to SW:ALSA_ECOLI (EMBL:U14003) Escherichia coli D-allose transport ATP-binding protein AlsA, 510 aa; fasta scores: opt: 1200 z-score: 1308.3 E(): 0; 40.7% identity in 514 aa overlap. Contains two Pfam matches to entry PF00005 ABC_tran, ABC transporter and two matches to Prosite entries PS00017 ATP/GTP-binding sit [...]
 
 0.914
SCO6010
SC7B7.07, probable ABC-transport system ATP binding protein, len: 260 aa; similar to many eg. XYLG_ECOLI P37388 d-xylose transport atp-binding protein (513 aa), fasta scores; opt: 567 z-score: 580.0 E(): 3.8e-25, 36.5% identity in 255 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature. Possible alternative start 9 bp upstream.
 
 0.883
SCO6571
SC3F9.06, possible DNA-binding protein, len: 332 aa; similar to TR:Q9A7T9 (EMBL:AE005838) Caulobacter crescentus hypothetical protein CC1631, 351 aa; fasta scores: opt: 552 Z-score: 641.5 E(): 4.2e-28; 34.940% identity in 332 aa overlap. Contains possible helix-turn-helix motif at residues 55 to 76 (Score 1148, +3.10 SD).
 
    0.802
SCO0808
SCF43.19c, possible secreted solute-binding lipoprotein, len: 360 aa. Similar to many bacterial extracellular solute-binding proteins including: Bacillus subtilis SW:RBSB_BACSU(EMBL:Z92953) D-ribose-binding protein precursor, RbsB (305 aa), fasta scores opt: 234 z-score: 252.1 E(): 1.2e-06 24.9% identity in 277 aa overlap and Streptomyces coelicolor TR:CAB56679(EMBL:AL121596) possible secreted solute-binding lipoprotein SCF51A.27 (359 aa), fasta scores opt: 1487 z-score: 1547.8 E(): 0 63.1% identity in 360 aa overlap. Contains an appropriately positioned Prosite hit to PS00013 Prokaryo [...]
 
 0.783
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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