Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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SCO7046Putative integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)    
Predicted Functional Partners:
SCO7044
Putative integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
  
 0.986
SCO7045
SC4G1.11, hypothetical protein, len: 114 aa; similar to TR:O59172 (EMBL:AP000006) Pyrococcus horikoshii hypothetical 14.9 kDa protein PH1503, 130 aa; fasta scores: opt: 302 z-score: 405.0 E(): 4.3e-15; 41.0% identity in 100 aa overlap; Belongs to the UPF0166 family.
 
   
 0.962
SCO7043
Hypothetical protein SC4G1.09; SC4G1.09, unknown, len: 110 aa. Highly hydrophilic.
  
  
 0.737
SCO7047
Putative transport integral membrane protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.697
SCO4094
Conserved hypothetical protein SCD25.30; SCD25.30, unknown, len: 116 aa. Highly similar to Mycobacterium tuberculosis TR:P96242 (EMBL; Z83864) hypothetical 15.0 KD protein (137 aa), fasta scores opt: 395 z-score: 500.7 E(): 1.5e-20 54.4% identity in 114 aa overlap. Contains a Prosite hit to PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
       0.544
SCO4185
SCD66.22, conserved hypothetical protein, len: 336 aa; highly similar to TR:Q54237 (EMBL:D63706) Streptomyces griseus ORF4 hypothetical protein, 328 aa; fasta scores: opt: 1654 z-score: 1801.0 E(): 0; 78.6% identity in 322 aa overlap and N-terminal domain identical to TR:Q9Z4H1 (EMBL:D63677) Streptomyces coelicolor ORF4 hypothetical protein (fragment), 142 aa. Contains 3x degenerate repeat at N-terminal domain: PS(H/Q).
       0.544
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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