STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO0154Hypothetical protein SCJ1.03c; SCJ1.03c, unknown,len:220 aa, similarity to Synechocystis sp. (strain PCC 6803) hypothetical 24.8 KD protein TR:P73776 (EMBL: D90909)(218 aa), fasta scores opt: 291 z-score: 344.1 E(): 8.3e-12 31.2% identity in 170 aa overlap and a weakly similar to Pseudomonas fluorescens SW:TIPB_PSEFL (EMBL; U44827) thiol:disulfide interchange protein TipB precursor (cytochrome C biogenesis protein TipB) (178 aa), fasta scores opt: 148 z-score: 181.8 E(): 0.0091 28.7% identity in 122 aa overlap. (220 aa)    
Predicted Functional Partners:
SCO0155
SCJ1.04, possible tetR family transcriptional regulatory protein, len: 204 aa, similarity to several E.coli proteins including uid operon repressor (gus operon repressor) SW:UIDR_ECOLI (EMBL:M14641)(196 aa), fasta scores opt: 170 z-score: 212.8 E(): 0.00017 25.5%identity in 184 aa overlap and the hypothetical transcriptional regulator SW:YDHM_ECOLI (EMBL: AE000260)(199 aa), fasta scores opt: 176 z-score: 219.8 E(): 7e-05 27.6% identity in 185 aa overlap. In addition to Lactococcus lactis (subsp. lactis) hypothetical protein SW:YPB3_LACLA (EMBL: X60456) (196 aa), fasta scores opt: 245 z [...]
 
     0.638
SCO2489
SC7A8.28, probable tetR-family transcriptional regulator, len: 194 aa; similar to TR:CAB53122 (EMBL:AL109962) Streptomyces coelicolor putative transcriptional regulatory protein SCJ1.04, aa; fasta scores: opt: 184 z-score: 231.2 E(): 1.7e-05; 30.9% identity in 162 aa overlap and to SW:YCFQ_ECOLI (EMBL:AE000211) Escherichia coli hypothetical transcriptional regulator in NDH-MFD intergenic region YcfQ, 210 aa; fasta scores: opt: 282 z-score: 348.3 E(): 5.2e-12; 32.3% identity in 192 aa overlap. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family and poss [...]
 
     0.424
SCO0153
SCJ1.02c, probable secreted protein, len: 195 aa, similar to Actinosynnema pretiosum auranticum hypothetical 20.0 KD protein TR:O69206 (EMBL:U33059) (190 aa), fasta scores, opt: 524 z-score: 529.6 E(): 3.9e-22; 43.2% identity in 192 aa overlap. Contains a possible N-terminal signal peptide sequence.
       0.409
SCO0507
Hypothetical protein SCF6.03c; SCF6.03c, unknown, len: 138 aa. Similar to the C-terminus of many hypothetical oxidoreductases e.g. Streptomyces coelicolor TR: CAB53280 (EMBL; AL109972) putative oxidoreductase SCJ9A.19C (311 aa), fasta scores opt: 307 z-score: 331.8 E(): 4.1e-11 44.4% identity in 126 aa overlap.
  
     0.403
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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