STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1162SCG8A.16, possible methyltransferase, len: 199 aa; similar to TR:Q55214 (EMBL:L35154) aklanonic acid methyltransferase from Streptomyces sp. (220 aa) fasta scores; opt: 228, z-score: 264.1, E(): 2.9e-07, 34.1% identity in 123 aa overlap. (199 aa)    
Predicted Functional Partners:
SCO1159
SCG8A.13c, cvnB3, hypothetical protein, len: 145 aa; strongly similar to many from Streptomyces coelicolor e.g. TR:Q9X835 (EMBL:AL049727) hypothetical 14.4 kD protein (139 aa) fasta scores; opt: 412, z-score: 512.5, E(): 4.2e-21, 52.8% identity in 127 aa overlap. Also strongly similar to neighbouring CDS SCG8A.09c. Contains Pfam match to entry PF01860 DUF42, Protein of unknown function.
       0.715
SCO1158
SCG8A.12c, cvnC3, hypothetical protein, len: 137 aa; strongly similar to many from Streptomyces coelicolor eg. TR:O86523 (EMBL:AL031124) hypothetical protein (132 aa) fasta scores; opt: 284, z-score: 351.0, E(): 4.2e-12, 42.6% identity in 129 aa overlap.
  
    0.690
SCO1157
SCG8A.11c, cvnD3, possible ATP/GTP binding protein (conserved), len: 204aa; strongly similar to many from Streptomyces coelicolor eg. TR:O86519 (EMBL:AL031124) putative ATP/GTP binding protein (174 aa) fasta scores; opt: 695, z-score: 846.0, E(): 0, 61.3% identity in 168 aa overlap. Also similar to others eg. TR:O67698 (EMBL:AE000759) hypothetical protein from Aquifex aeolicus (186 aa) fasta scores; opt: 341, z-score: 420.7, E(): 5.5e-16, 37.1% identity in 175 aa overlap. Contains Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop).
       0.676
SCO1160
SCG8A.14c, cvnA3, possible membrane protein, len: 862 aa; similar to many from Streptomyces coelicolor e.g. TR:Q9X836 (EMBL:AL049727) putative large secreted protein (877 aa) fasta scores; opt: 1248, z-score: 1146.3, E(): 0, 34.7% identity in 836 aa overlap. Contains possible membrane-spanning hydrophobic regions.
  
    0.675
SCO0648
SCF91.08, possible methyltransferase, len: 231 aa. Similar in parts to several including: Streptomyces avermitilis TR:BAA84602(EMBL:AB032524) C5-O-methyltransferase (283 aa), fasta scores opt: 243 z-score: 292.9 E(): 6.1e-09 34.5% identity in 168 aa overlap and Streptomyces lavendulae TR:AAD28458(EMBL:AF127374) methyltransferase (275 aa), fasta scores opt: 235 z-score: 283.7 E(): 2e-08 32.9% identity in 167 aa overlap.
  
     0.651
SCO1161
SCG8A.15c, probable integral membrane protein, len: 244aa; N-terminal region similar to that of TR:CAB76246 (EMBL:X82447) CoxC protein from Pseudomonas carboxydovorans (402 aa) fasta scores; opt: 387, z-score: 455.6, E(): 6.2e-18, 34.6% identity in 243 aa overlap. Contains possible membrane-spanning hydrophobic regions.
       0.574
SCO1155
SCG8A.09c, conserved hypothetical protein, len: 137aa; strongly similar to many from Streptomyces coelicolor eg. TR:Q9X835 (EMBL:AL049727) hypothetical 14.4 kD protein (139 aa) fasta scores; opt: 366, z-score: 458.5, E(): 4.3e-18, 48.0% identity in 127 aa overlap. Also strongly similar to neighbouring CDS SCG8A.13c. Contains Pfam match to entry PF01860 DUF42, Protein of unknown function.
       0.560
SCO1164
Hypothetical protein; SCG8A.18, unknown, len: 108aa.
       0.560
SCO1165
SCG8A.19, possible integral membrane protein, len: 305aa; Contains possible membrane-spanning hydrophobic regions.
       0.560
SCO1154
Hypothetical protein; SCG8A.08c, unknown, len: 323aa.
       0.482
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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