Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCO1519 | SCO1520 | gene:17759105 | gene:17759106 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | 0.999 |
| SCO1519 | SCO1521 | gene:17759105 | gene:17759107 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.11c, hypothetical protein, len: 250 aa; similar to various hypothetical proteins, e.g. TR:YQ03_MYCTU (EMBL:Z98045) Mycobacterium tuberculosis hypothetical 26.8 kD protein RV2603c, 251 aa; fasta scores: opt: 1268 z-score: 1388.1 E(): 0; 76.7% identity in 249 aa overlap. Contains Pfam match to entry PF01709 DUF28, Domain of unknown function. | 0.856 |
| SCO1519 | SCO1522 | gene:17759105 | gene:17759108 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Conserved hypothetical protein SCL2.12c; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.736 |
| SCO1519 | SCO1523 | gene:17759105 | gene:17759109 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Conserved hypothetical protein SCL2.13c; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.733 |
| SCO1519 | SCO1524 | gene:17759105 | gene:17759110 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.14c, putative membrane protein, len: 180 aa; similar to TR:O06205 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 38.1 Kd protein MTCY1A10.24, 351 aa; fasta scores: opt: 179 z-score: 211.7 E(): 0.00021; 43.3% identity in 171 aa overlap. Contains possible hydrophobic membrane spanning region. | 0.680 |
| SCO1519 | SCO1525 | gene:17759105 | gene:17759111 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.15c, possible sugar transferase, len: 387 aa; similar to TR:O28546 (EMBL:AE000983) Archaeoglobus fulgidus galactosyltransferase, 356 aa; fasta scores: opt: 422 z-score: 488.7 E(): 7.9e-20; 26.9% identity in 375 aa overlap and to TR:O06204 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 40.4 Kd protein MTCY1A10.23, 378 aa; fasta scores: opt: 1216 z-score: 1400.3 E(): 0; 52.7% identity in 376 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1. | 0.658 |
| SCO1519 | SCO1526 | gene:17759105 | gene:17759112 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.16c, possible acyltransferase, len: 311 aa; similar to TR:Q9Z983 (EMBL:AE001596) Chlamydia pneumoniae acyltransferase HtrB, 467 aa; fasta scores: opt: 243 z-score: 289.8 E(): 9.4e-09; 29.0% identity in 238 aa overlap and to SW:HTRB_ECOLI (EMBL:X61000) Escherichia coli lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) HtrB, 306 aa; fasta scores: opt: 130 z-score: 159.2 E(): 0.18; 23.4% identity in 286 aa overlap. | 0.658 |
| SCO1519 | SCO1527 | gene:17759105 | gene:17759113 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.17c, possible membrane transferase, len: 241 aa; similar to TR:CAB50482 (EMBL:AJ248288) Pyrococcus abyssi CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA, 186 aa; fasta scores: opt: 286 z-score: 350.3 E(): 4e-12; 33.0% identity in 203 aa overlap and to TR:O06202 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 23.3 kD protein MTCY1A10.21, 217 aa; fasta scores: opt: 564 z-score: 679.1 E(): 2e-30; 43.4% identity in 212 aa overlap. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase and match to Prosite entry PS00379 [...] | 0.666 |
| SCO1519 | SCO1528 | gene:17759105 | gene:17759114 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.18, possible elongation factor, len: 732 aa; similar to TR:O07170 (EMBL:Z96071) Mycobacterium tuberculosis FusA2, 714 aa; fasta scores: opt: 2328 z-score: 2349.0 E(): 0; 61.4% identity in 731 aa overlap, to SW:EFG (EMBL:X00415) Escherichia coli elongation factor G (EF-G) FusA, 703 aa; fasta scores: opt: 853 z-score: 862.2 E(): 0; 30.1% identity in 722 aa overlap and to SW:EFG2_STRCO (EMBL:AL031013) Streptomyces coelicolor elongation factor G 2 (EF-G 2), FusB, 686 aa; fasta scores: opt: 937 z-score: 947.0 E(): 0; 35.5% identity in 710 aa overlap. Contains Pfam matches to entries PF [...] | 0.667 |
| SCO1519 | SCO1529 | gene:17759105 | gene:17759115 | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | SCL2.19, possible membrane protein, len: 551 aa. Contains possible hydrophobic membrane spanning regions. | 0.602 |
| SCO1520 | SCO1519 | gene:17759106 | gene:17759105 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.999 |
| SCO1520 | SCO1521 | gene:17759106 | gene:17759107 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.11c, hypothetical protein, len: 250 aa; similar to various hypothetical proteins, e.g. TR:YQ03_MYCTU (EMBL:Z98045) Mycobacterium tuberculosis hypothetical 26.8 kD protein RV2603c, 251 aa; fasta scores: opt: 1268 z-score: 1388.1 E(): 0; 76.7% identity in 249 aa overlap. Contains Pfam match to entry PF01709 DUF28, Domain of unknown function. | 0.857 |
| SCO1520 | SCO1522 | gene:17759106 | gene:17759108 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | Conserved hypothetical protein SCL2.12c; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.736 |
| SCO1520 | SCO1523 | gene:17759106 | gene:17759109 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | Conserved hypothetical protein SCL2.13c; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.733 |
| SCO1520 | SCO1524 | gene:17759106 | gene:17759110 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.14c, putative membrane protein, len: 180 aa; similar to TR:O06205 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 38.1 Kd protein MTCY1A10.24, 351 aa; fasta scores: opt: 179 z-score: 211.7 E(): 0.00021; 43.3% identity in 171 aa overlap. Contains possible hydrophobic membrane spanning region. | 0.680 |
| SCO1520 | SCO1525 | gene:17759106 | gene:17759111 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.15c, possible sugar transferase, len: 387 aa; similar to TR:O28546 (EMBL:AE000983) Archaeoglobus fulgidus galactosyltransferase, 356 aa; fasta scores: opt: 422 z-score: 488.7 E(): 7.9e-20; 26.9% identity in 375 aa overlap and to TR:O06204 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 40.4 Kd protein MTCY1A10.23, 378 aa; fasta scores: opt: 1216 z-score: 1400.3 E(): 0; 52.7% identity in 376 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1. | 0.658 |
| SCO1520 | SCO1526 | gene:17759106 | gene:17759112 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.16c, possible acyltransferase, len: 311 aa; similar to TR:Q9Z983 (EMBL:AE001596) Chlamydia pneumoniae acyltransferase HtrB, 467 aa; fasta scores: opt: 243 z-score: 289.8 E(): 9.4e-09; 29.0% identity in 238 aa overlap and to SW:HTRB_ECOLI (EMBL:X61000) Escherichia coli lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) HtrB, 306 aa; fasta scores: opt: 130 z-score: 159.2 E(): 0.18; 23.4% identity in 286 aa overlap. | 0.658 |
| SCO1520 | SCO1527 | gene:17759106 | gene:17759113 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.17c, possible membrane transferase, len: 241 aa; similar to TR:CAB50482 (EMBL:AJ248288) Pyrococcus abyssi CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA, 186 aa; fasta scores: opt: 286 z-score: 350.3 E(): 4e-12; 33.0% identity in 203 aa overlap and to TR:O06202 (EMBL:Z95387) Mycobacterium tuberculosis hypothetical 23.3 kD protein MTCY1A10.21, 217 aa; fasta scores: opt: 564 z-score: 679.1 E(): 2e-30; 43.4% identity in 212 aa overlap. Contains Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase and match to Prosite entry PS00379 [...] | 0.658 |
| SCO1520 | SCO1528 | gene:17759106 | gene:17759114 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.18, possible elongation factor, len: 732 aa; similar to TR:O07170 (EMBL:Z96071) Mycobacterium tuberculosis FusA2, 714 aa; fasta scores: opt: 2328 z-score: 2349.0 E(): 0; 61.4% identity in 731 aa overlap, to SW:EFG (EMBL:X00415) Escherichia coli elongation factor G (EF-G) FusA, 703 aa; fasta scores: opt: 853 z-score: 862.2 E(): 0; 30.1% identity in 722 aa overlap and to SW:EFG2_STRCO (EMBL:AL031013) Streptomyces coelicolor elongation factor G 2 (EF-G 2), FusB, 686 aa; fasta scores: opt: 937 z-score: 947.0 E(): 0; 35.5% identity in 710 aa overlap. Contains Pfam matches to entries PF [...] | 0.633 |
| SCO1520 | SCO1529 | gene:17759106 | gene:17759115 | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | SCL2.19, possible membrane protein, len: 551 aa. Contains possible hydrophobic membrane spanning regions. | 0.602 |
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