STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1896Conserved hypothetical protein; SCI7.14, unknown, len: 269aa; similar to many eg. SW:YTBQ_BACSU hypothetical protein from Bacillus subtilis (253 aa) fasta scores; opt: 262, z-score: 310.1, E(): 6.1e-10, (27.8% identity in 241 aa overlap). (269 aa)    
Predicted Functional Partners:
SCO1894
SCI7.12c, alanine-rich protein, len: 390aa.
 
    0.876
SCO1895
SCI7.13c, probable dihydropicolinate synthase, len: 316 aa; similar to many egs. SW:KDGD_PSEPU 5-dehydro-4-deoxyglutarate dehydratase from Pseudomonas putida (303 aa) fasta scores; opt: 731, z-score: 838.6, E(): 0, (41.1% identity in 302 aa overlap) and SW:DAPA_BACSU dihydropicolinate synthase from Bacillus subtilis (290 aa) fasta scores; opt: 374, z-score: 432.9, E(): 8.8e-17, (29.2% identity in 288 aa overlap). Contains Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase family.
 
   
 0.750
SCO4659
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS12 family.
   
 0.728
SCO4706
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.727
SCO4708
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.726
SCO4711
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.721
SCO1898
SCI7.16, possible sugar binding protein, len: 456aa; similar to many eg. TR:O30831 (EMBL:AF018073) periplasmic sorbitol binding protein from Rhodobacter sphaeroides (436 aa) fasta scores; opt: 1203, z-score: 1347.3, E(): 0, (42.8% identity in 423 aa overlap). Contains possible N-terminal signal sequence.
 
     0.719
SCO4719
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
 0.715
SCO4716
30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 0.713
SCO5736
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
  0.702
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.