STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1992SC7H2.06c, possible integral membrane protein, len: 168aa; contains possible membrane spanning hydrophobic regions. (168 aa)    
Predicted Functional Partners:
SCO1993
Hypothetical protein; SC7H2.07c, unknown, len: 228aa.
 
     0.859
SCO1994
SC7H2.08, possible integral membrane protein, len: 118aa; contains possible membrane spanning hydrophobic region.
  
   0.749
SCO6045
Hypothetical protein SC1B5.05c; SC1B5.05c, unknown, len: 438 aa; slight similarity to hypothetical protein from Haemophilus influenzae YG00_HAEIN P44268 (317 aa), fasta scores; opt: 252 z-score: 283.4 E(): 1.5e-08, 26.8% identity in 298 aa overlap; In the N-terminal section; belongs to the UPF0276 family.
  
  
 0.502
SCP1.261c
SCP1.261c, possible secreted protein, len: 167aa; N-terminus strongly similar to that from TR:Q9S1W2 (EMBL:AL109950) hypothetical protein SCJ4.11 from Streptomyces coelicolor. Contains a possible cleavable N-terminal signal sequence.
 
    0.495
SCO5077
SCBAC28G1.03, actVA2, hypothetical protein, len: 131 aa; identical to previously sequenced TR:Q53904 (EMBL:X58833) Streptomyces coelicolor 6 ActVA region genes of the actinorhodin biosynthetic gene cluster, ActVA2, 131 aa.
  
     0.446
SCO1714
SCI11.03c, possible secreted protein, len: 189 aa; unknown function, probable CDS suggested by GC frameplot, positional base preference and amino acid composition. Contains a probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site, so may be a lipoprotein.
 
    0.429
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.