STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO2423SCC42.04, possible secreted protein, len: 210 aa. Contains possible N-terminal region signal peptide sequence. (210 aa)    
Predicted Functional Partners:
SCO2415
SC8A2.03c, possible secreted protein, len: 413 aa; similar to TR:O53971 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 40.2 kDa protein MTV051.08, 377 aa; fasta scores: opt: 685 z-score: 681.0 E(): 2.1e-30; 36.0% identity in 311 aa overlap. Contains Pfam match to entry PF02470 mce. Also contains possible N-terminal region signal peptide sequence.
     
 0.797
SCO2422
SCC42.03c, possible ABC-transporter ATP-binding protein, len: 343 aa; similar to SW:YRBF_HAEIN (EMBL:U32788) Haemophilus influenzae hypothetical ABC-transporter ATP-binding protein HI1087, 264 aa; fasta scores: opt: 680 z-score: 686.6 E(): 8.9e-31; 41.4% identity in 244 aa overlap. Contains Pfam match to entry PF00005 ABC_tran, ABC transporter and matches to Prosite entries PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature.
     
 0.768
SCO2424
SCC42.05, possible secreted protein, len: 533 aa. Contains possible N-terminal region signal peptide sequence. High content in alanine amino acid residues.
       0.764
SCO2425
SCC42.06, possible secreted protein, len: 313 aa. Contains possible N-terminal region signal peptide sequence.
       0.735
SCO2420
SCC42.01c, possible ABC-transporter integral membrane protein (fragment), len: >161 aa; similar to TR:O53545 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 29.6 kD protein MTV023.07c, 280 aa; fasta scores: opt: 565 z-score: 630.0 E(): 1.3e-27; 54.5% identity in 154 aa overlap. Contains possible hydrophobic membrane spanning regions; SC8A2.08c, conserved hypothetical protein (fragment), len: >139 aa; similar to TR:O53966 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 28.1 kDa protein MTV051.03, 271 aa; fasta scores: opt: 474 z-score: 595.0 E(): 1.3e-25; 48.6% identity [...]
     
 0.716
SCO2421
SCC42.02c, possible ABC-transporter integral membrane protein, len: 254 aa; similar to TR:O53546 (EMBL:AL022022) Mycobacterium tuberculosis hypothetical 26.6 kD protein MTV023.08c, 254 aa; fasta scores: opt: 881 z-score: 1004.0 E(): 0; 50.8% identity in 242 aa overlap. Contains possible hydrophobic membrane spanning regions.
     
 0.709
SCO2414
SC8A2.02c, possible secreted protein, len: 433 aa; similar to TR:O53972 (EMBL:AL022073) Mycobacterium tuberculosis hypothetical 46.7 kDa protein MTV051.09, 437 aa; fasta scores: opt: 529 z-score: 488.9 E(): 1e-19; 31.3% identity in 438 aa overlap. Contains Pfam match to entry PF02470 mce. Also contains possible N-terminal region signal peptide sequence.
     
 0.703
SCO2419
SC8A2.07c, possible secreted protein, len: 418 aa; similar to TR:O53967 (EMBL:AL022073) Mycobacterium tuberculosis mce-family protein MTV051.04, 425 aa; fasta scores: opt: 548 z-score: 564.7 E(): 6.2e-24; 33.0% identity in 367 aa overlap. Contains Pfam match to entry PF02470 mce. Also contains possible N-terminal region signal peptide sequence.
     
 0.547
SCO3013
SCE33.15c, probable two-component system response regulator, len: 229 aa; similar to TR:Q50447 (EMBL:Z95121) Mycobacterium tuberculosis MtrA, 228 aa; fasta scores: opt: 1141 z-score: 1397.7 E(): 0; 74.9% identity in 227 aa overlap, to SW:AFQ1_STRCO (EMBL:D10654) Streptomyces coelicolor transcriptional regulatory protein AfsQ1, 225 aa; fasta scores: opt: 698 z-score: 858.5 E(): 0; 47.7% identity in 220 aa overlap and to many other S. coelicolor two-component system response regulators, e.g. TR: CAB77324(EMBL:AL160331) putative response regulator SCD8A.03, 223 aa; fasta scores: opt: 695 [...]
      
 0.483
SCO3011
SCE33.13c, possible lipoprotein, len: 615 aa; similar to TR:O05889 (EMBL:Z95121) Mycobacterium tuberculosis hypothetical 61.2 kD protein MTCY20B11.19c, 583 aa; fasta scores: opt: 228 z-score: 243.7 E(): 4.1e-06; 25.5% identity in 624 aa overlap. Contains properly located match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site and possible N-terminal region signal peptide sequence.
      
 0.410
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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