STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO2434SCC24.05c, possible sugar transporter sugar binding protein, len: 452 aa; similar to TR:CAB59595 (EMBL:AL132662) Streptomyces coelicolor, probable sugar transporter sugar binding lipoprotein SCF11.18, 442 aa; fasta scores: opt: 274 z-score: 320.2 E(): 2.1e-10; 23.3% identity in 443 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Contains possible N-terminal signal peptide sequence. (452 aa)    
Predicted Functional Partners:
SCO2431
SCC24.02c, abfA, alpha-L-arabinofuranosidase, len: 501 aa; almost identical to SW:ABFA_STRLI (EMBL:U04630) Streptomyces lividans alpha-L-arabinofuranosidase (EC 3.2.1.55) AbfA, 662 aa.
 
  
 0.912
SCO2432
SCC24.03c, possible sugar transporter membrane protein, len: 287 aa; similar to TR:CAB59597 (EMBL:AL132662) Streptomyces coelicolor probable sugar transport inner membrane protein SCF11.20, 299 aa; fasta scores: opt: 673 z-score: 788.9 E(): 0; 35.3% identity in 278 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions.
 
 
 0.910
SCO2433
SCC24.04c, possible sugar transporter membrane protein, len: 313 aa; similar to TR: CAB59596(EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 533 z-score: 637.4 E(): 4.5e-28; 36.2% identity in 304 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions.
 
 
 0.907
SCO1056
SCG22.02, possible sugar transport sugar binding protein, len: 419 aa; similar to TR:CAB90879 (EMBL:AL355752) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa; fasta scores: opt: 433 z-score: 507.0 E(): 9.2e-21; 28.7% identity in 380 aa overlap and to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 255 z-score: 299.6 E(): 3.3e-09; 23.9% identity in 372 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and correctly situ [...]
  
   
 0.703
SCO1539
Putative lipoprotein; SCL2.29c, possible secreted protein, len: 433 aa; similar to TR:O31518 (EMBL:Z99107) Bacillus subtilis YesO protein, 412 aa; fasta scores: opt: 606 z-score: 680.7 E(): 1.7e-30; 27.7% identity in 411 aa overlap and to TR:CAB59595 (EMBL:AL132662) Streptomyces coelicolor probable sugar transporter sugar binding lipoprotein SCF11.18, 442 aa; fasta scores: opt: 312 z-score: 352.1 E(): 3.4e-12; 24.4% identity in 454 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and match to Prosite entry PS00013 Prokaryo [...]
  
   
 0.697
SCO7505
SCBAC17A6.38, possible integral membrane binding-protein-dependent transport protein, len: 299aa; similar to many eg. TR:Q9L0B4 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 905, Z-score: 1049.4, 50.000% identity (51.799% ungapped) in 288 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...]
 
 
 0.693
SCO7504
SCBAC17A6.37, possible integral membrane binding-protein-dependent transport protein, len: 316aa; similar to many eg. TR:Q9L0B3 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 949, Z-score: 1058.2, 48.867% identity (50.671% ungapped) in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...]
 
 
 0.678
SCO0271
SCF1.13, possible binding-protein-dependent transport protein, len: 317aa; similar to many predicted membrane transporters eg. TR:CAB41203 (EMBL:AL049661) putative binding-protein-dependent transport protein from Streptomyces coelicolor (327 aa) fasta scores; opt: 624, z-score: 720.7, E(): 8.8e-33, (35.9% identity in 320 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component, Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible membrane spanning hydrophobic [...]
 
 
 0.650
SCO3484
SCE65.20c, possible secreted sugar-binding protein, len: 436 aa; similar to TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa; fasta scores: opt: 361 z-score: 398.4 E(): 8.1e-15; 26.2% identity in 409 aa overlapand to TR:O87856 (EMBL:AL031013) Streptomyces coelicolor putative secreted sugar binding protein SC8A6.22, 438 aa; fasta scores: opt: 344 z-score: 379.6 E(): 9e-14; 23.6% identity in 365 aa overlap. Contains match to Pfam entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and match to Prosite entry correctly [...]
  
   
 0.624
SCO1538
SCL2.28c, probable transport system membrane protein, len: 328 aa; similar to SW:YESP_BACSU (EMBL:Z99107) Bacillus subtilis probable ABC transporter permease protein YesP, 309 aa; fasta scores: opt: 1013 z-score: 1146.0 E(): 0; 48.8% identity in 301 aa overlap and to TR:CAB59596 (EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 608 z-score: 690.8 E(): 4.4e-31; 32.8% identity in 320 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component [...]
 
   0.584
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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