STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO2458SCC24.29c, hypothetical protein, len: 172 aa; similar to TR:Q9X8S3 (EMBL:AL049754) Streptomyces coelicolor hypothetical 20.1 kD protein SCH10.34c, 185 aa; fasta scores: opt: 412 z-score: 505.6 E(): 1e-20; 40.7% identity in 172 aa overlap. (172 aa)    
Predicted Functional Partners:
SCO2456
SCC24.27c, possible integral membrane protein, len: 146 aa; similar to SW:Y0B1_MYCTU (EMBL:Z77724) Mycobacterium tuberculosis hypothetical 13.7 kD protein CY227.01c, MTCY227.01c, 133 aa; fasta scores: opt: 241 z-score: 297.9 E(): 3.7e-09; 34.8% identity in 135 aa overlap. Contains possible hydrophobic membrane spanning regions.
 
     0.947
SCO2457
SCC24.28c, possible lipoprotein, len: 131 aa; similar to SW:Y0B2_MYCTU (EMBL:Z77724) Mycobacterium tuberculosis hypothetical 15.0 kD protein CY227.02c precursor, MTCY227.02c, 143 aa; fasta scores: opt: 130 z-score: 169.2 E(): 0.054; 26.5% identity in 136 aa overlap. Contains match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attachment site and possible N-terminal region signal peptide sequence.
       0.875
SCO2455
Putative spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
     0.869
SCO3655
Putative spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
     0.752
SCO7257
Putative secreted protein; One of 8 partially redundant surface-active proteins required for efficient formation of aerial mycelium; the short chaplins assemble into a hydrophobic, amyloidal fibrillar surface layer that envelopes and protects aerial hyphae and spores, presumably anchored to the long chaplins. Chaplins have an overlapping function with the surface-active SapB peptide; chaplins are essential on minimal medium while on rich medium both chaplins and SapB are required for efficient aerial hyphae formation. The long chaplins (ChpA, ChpB, ChpC) are not absolutely necessary fo [...]
  
     0.621
SCO4400
SCD10.32, possible membrane protein, len: 531 aa. Contains possible hydrophobic membrane spanning region and high content in alanine, glycine and proline amino acid residues. Also high G+C content (79.03%) and a 3x degenerate repeat unit: GGR.
  
     0.614
SCO2716
Putative secreted protein; One of 8 partially redundant surface-active proteins required for efficient formation of aerial mycelium; the short chaplins assemble into a hydrophobic, amyloidal fibrillar surface layer that envelopes and protects aerial hyphae and spores, presumably anchored to the long chaplins. Chaplins have an overlapping function with the surface-active SapB peptide; chaplins are essential on minimal medium while on rich medium both chaplins and SapB are required for efficient aerial hyphae formation. A minimal chaplin strain capable of forming aerial mycelium/hyphae o [...]
  
     0.594
SCO1674
Putative secreted protein; One of 8 partially redundant surface-active proteins required for efficient formation of aerial mycelium; the short chaplins assemble into a hydrophobic, amyloidal fibrillar surface layer that envelopes and protects aerial hyphae and spores, presumably anchored to the long chaplins. Chaplins have an overlapping function with the surface-active SapB peptide; chaplins are essential on minimal medium while on rich medium both chaplins and SapB are required for efficient aerial hyphae formation. A minimal chaplin strain capable of forming aerial mycelium/hyphae o [...]
  
     0.580
SCO4398
SCD10.30c, conserved hypothetical protein, len: 217 aa; similar to TR:Q9ZBP8 (EMBL:AL034447) Streptomyces coelicolor hypothetical 23.3 kD protein SC7A1.25c, 223 aa; fasta scores: opt: 514 z-score: 621.6 E(): 3.8e-27; 45.0% identity in 189 aa overlap.
  
     0.552
SCO2459
Hypothetical protein SCC24.30c; SCC24.30, unknown, len: 177 aa.
       0.538
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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