STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO3861SCH69.31c, putative membrane protein, len: 441 aa. Contains possible hydrophobic membrane spanning regions. (441 aa)    
Predicted Functional Partners:
SCO3862
SCH69.32c, putative membrane protein, len: 93 aa. Contains possible hydrophobic membrane spanning region.
       0.768
SCO5248
2SC7G11.10c, hypothetical protein, len: 192 aa; similar to TR:O06288 (EMBL:Z95557) Mycobacterium tuberculosis hypothetical 30.6 kDa protein MTCY07H7.28c, 275 aa; fasta scores: opt: 180 z-score: 221.9 E(): 6.8e-05; 31.8% identity in 176 aa overlap.
  
     0.753
SCO5397
SC8F4.01c, large Ala/Glu-rich protein, len: 1326 aa; hydrophilic with strong potential for coiled-coil structure throughout.
  
     0.732
SCO4957
2SCK31.17c, putative membrane protein, len: 372 aa; similar to TR:Q9S2T3 (EMBL:AL096884) Streptomyces coelicolor hypothetical 40.5 kDa protein SC4G6.25, 376 aa; fasta scores: opt: 334 z-score: 393.9 E(): 2.1e-14 34.3% identity in 324 aa overlap. Contains possible hydrophobic membrane spanning region.
  
     0.731
SCO4960
2SCK31.20c, possible sigma factor, len: 168 aa; similar to SW:RPOE_STRCO (EMBL:L29636) Streptomyces coelicolor RNA polymerase sigma-E factor SigE, 176 aa; fasta scores: opt: 108 z-score: 140.1 E(): 2.9; 30.8% identity in 156 aa overlap.
  
     0.716
SCO4390
SCD10.22, hypothetical protein, len: 467 aa; similar to TR:CAB92197 (EMBL:AL356592) Streptomyces coelicolor hypothetical 84.7 kD protein SC9H11.08, 802 aa; fasta scores: opt: 261 z-score: 286.0 E(): 1.9e-08; 29.2% identity in 463 aa overlap. Contains 2 Pfam matches to entry PF00989 PAS, PAS domain and Pfam match to entry PF00785 PAC, PAC motif.
  
     0.701
SCO1832
SCI8.17c, possible membrane protein, len: 192 aa. Contains a possible N-terminal signal sequence and a possible membrane spanning hydrophobic domain.
  
     0.698
SCO3863
SCH69.33, putative secreted protein, len: 129 aa; similar to TR:CAA09663 (EMBL:AJ011500) hypothetical protein from the granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22 (124 aa) fasta scores; opt: 259, z-score: 293.5, E(): 5.1e-09, (41.5% identity in 118 aa overlap). Contains possible N-terminal region signal peptide sequence.
       0.698
SCO2356
SCC8A.14, possible membrane protein, len: 467aa; contains a possible membrane-spanning hydrophobic region close to the N-terminus.
 
    0.681
SCO3859
SCH69.29, possible DNA-binding protein, len: 182 aa; highly similar to TR:CAA09629 (EMBL:AJ011500) hypothetical protein from granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22 (182 aa) fasta scores; opt: 1045, z-score: 1158.8, E(): 0, (90.1% identity in 182 aa overlap). Contains probable helix-turn-helix 38-59aa (+3.20 SD).
  
     0.672
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.