STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO40332SC10A7.37, possible membrane protein, len: 96 aa. Contains possible hydrophobic membrane spanning region at C-terminal domain. (96 aa)    
Predicted Functional Partners:
SCO6904
SC1B2.10, possible membrane protein, len: 336 aa.Contains a possible membrane spanning hydrophobic domain. Rich in the amino acid Threonine.
     
 0.803
SCO1431
Putative membrane protein; SC6D7.08, possible membrane protein, len: 80 aa. Contains a possible membrane spanning hydrophobic domain.
      
 0.785
SCO2199
SC3H12.07, possible integral membrane protein, len: 89 aa; identical to previously sequenced TR:CAB51283 (EMBL:AL096872) Streptomyces coelicolor hypothetical protein SC5F7.02, 89 aa. Contains possible hydrophobic membrane spanning regions.
      
 0.785
SCO3860
SCH69.30, possible serine/threonine protein kinase, len: 576 aa; similar to many e.g. TR:CAA09628 (EMBL:AJ011500) putative serine/threonine protein kinase from the granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22 (433 aa) fasta scores; opt: 1791, z-score: 976.0, E(): 0, (65.2% identity in 428 aa overlap) and SW:PKAA_STRCO PkaA, serine/threonine protein kinase (543 aa) fasta scores; opt: 576, z-score: 329.1, E(): 5.2e-11, (29.6% identity in 564 aa overlap). Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains possible hydrophobi [...]
      
 0.785
SCO4174
SCD66.11c, possible integral membrane protein, len: 83 aa. Contains possible hydrophobic membrane spanning region.
      
 0.785
SCO5157
SCP8.20c, probable metal-transport protein, len: 371 aa; similar to TR:O50455 (EMBL:AL021006) Mycobacterium tuberculosis putative magnesium and cobalt transport protein MTV006.11c, 366 aa; fasta scores: opt: 1137 z-score: 1293.8 E(): 0; 47.8% identity in 370 aa overlap and to SW:CORA_ECOLI (EMBL:L11042) Escherichia coli magnesium and cobalt transport protein CorA, 316 aa; fasta scores: opt: 211 z-score: 245.7 E(): 3.2e-06; 23.2% identity in 306 aa overlap. Contains Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein and possible hydrophobic membrane spanning region at [...]
      
 0.785
SCO5344
SCBAC5H2.13, spdD2 protein, len: 107 aa; highly similar to plasmid borne TR:Q07196 (EMBL:AJ005260) Streptomyces ambofaciens probably involved in pSAM2 spreading (intramycelial transfer) SpdD protein, 104 aa; fasta scores: opt: 517 z-score: 454.5 E(): 9.7e-18; 74.5% identity in 106 aa overlap and to TR:Q9X8C6 (EMBL:AL049573) Streptomyces coelicolor SpdD protein, 105 aa; fasta scores: opt: 485 z-score: 428.0 E(): 2.9e-16; 70.6% identity in 109 aa overlap. Contains possible hydrophobic membrane spanning regions.
      
 0.785
SCO7330
Putative membrane protein; SC4G10.09, possible membrane protein, len: 78 aa. Contains a possible membrane spanning hydrophobic domain.
      
 0.785
SCO4032
2SC10A7.36c, probable marR regulatory protein, len: 166 aa; similar to SW:MARR_ECOLI (EMBL:M96235) Escherichia coli multiple antibiotic resistance protein MarR, 125 aa; fasta scores: opt: 164 z-score: 211.9 E(): 0.00027; 27.3% identity in 110 aa overlap. Contains Pfam match to entry PF01047 MarR, MarR family.
       0.775
SCO2973
SCE59.32c, pkaB, serine/threonine protein kinase (partial), len: >233 aa; identical to C-terminal region of previously sequenced SW:PKAB_STRCO (EMBL:D86821) Streptomyces coelicolor serine/threonine protein kinase PkaB, 417 aa. Contains Pfam match to entry PF00069 pkinase, Eukaryotic protein kinase domain. Contains possible hydrophobic membrane spanning region; SCE50.01, pkaB, serine/threonine protein kinase (fragment), len: >222 aa; identical to C-terminal region of previously sequenced SW:PKAB_STRCO (EMBL:D86821) Streptomyces coelicolor serine/threonine protein kinase PkaB (EC 2.7.1.- [...]
      
 0.740
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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