STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SCO4240ABC transporter ATP-binding protein; Part of the ABC transporter complexes DasABC-MsiK and NgcEFG- MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for energy coupling to the transport system. (378 aa)    
Predicted Functional Partners:
SCO2229
SC10B7.24c, malG, putative maltose permease, len: 303 aa; identical to previously sequenced TR:P72399 (EMBL:Y07706) Streptomyces coelicolor putative maltose permease MalG, 302 aa and similar to SW:MALG_ECOLI (EMBL:X02871) Escherichia coli maltose transport system permease protein MalG, 296 aa; fasta scores: opt: 476 z-score: 570.0 E(): 2.3e-24; 34.1% identity in 293 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane [...]
 
 0.997
SCO2231
SC10B7.26c, malE, putative maltose-binding protein, len: 423 aa; identical to previously sequenced TR:P72397 (EMBL:Y07706) Streptomyces coelicolor putative maltose-binding protein MalE, 423 aa and similar to SW:MALX_STRPN (EMBL:L08611) Streptococcus pneumoniae maltose/maltodextrin-binding protein precursor MalX, 423 aa; fasta scores: opt: 431 z-score: 470.1 E(): 8.4e-19; 28.1% identity in 434 aa overlap. Contains Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein and two matches to Prosite entries PS00013 Prokaryotic membrane lipoprotein lipid a [...]
 
 0.990
SCO5232
Putative sugar transporter sugar binding protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Binds specifically to (GlcNAc)2. Can also bind to GlcNAc, (GlcNAc)3, (GlcNAc)4 and (GlcNAc)5, but it exhibits the highest affinity for (GlcNAc)2. Involved in the control of morphological differentiation.
  
 0.989
SCO0533
SCF11.13, possible sugar transporter membrane protein, len: 285 aa; similar to TR:CAB46387 (EMBL:AL096743) Streptomyces coelicolor putative integral membrane transport protein MalG, 296 aa; fasta scores: opt: 538 z-score: 675.0 E(): 3.2e-30; 33.7% identity in 279 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature.
 
 0.988
SCO2944
SCE59.03c, possible sugar transporter membrane protein, len: 281 aa; similar to TR:CAB59590 (EMBL:AL132662) Streptomyces coelicolor putative sugar transporter inner membrane protein SCF11.13, 285 aa; fasta scores: opt: 730 z-score: 883.7 E(): 0; 42.1% identity in 278 aa overlap and to TR:AAF11008 (EMBL:AE001988) Deinococcus radiodurans ABC transporter, permease protein, MalFG family DR1436, 283 aa; fasta scores: opt: 645 z-score: 781.7 E(): 0; 38.2% identity in 272 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane co [...]
 
 0.988
SCO5234
Putative sugar transporter integral membrane protein; Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family.
 
 0.988
SCO7166
SC9A4.28c, probable sugar-transporter integral membrane protein, len: 310 aa; similar to TR:Q9RJV7 (EMBL:AL117387) Streptomyces coelicolor putative binding protein dependent transport protein SCF41.12, 303 aa; fasta scores: opt: 913 z-score: 1073.6 E(): 0; 46.9% identity in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions.
 
 0.971
SCO1900
SCI7.18, possible integral membrane sugar transport protein, len: 292aa; similar to many eg. TR:O30833 (EMBL:AF018073) sorbitol/mannitol transport inner membrane protein from Rhodobacter sphaeroides (276 aa) fasta scores; opt: 659, z-score: 770.4, E(): 0, (40.6% identity in 276 aa overlap). Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Also contains possible membrane spanning hydrophobic regions.
 
 0.970
SCO6006
Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.968
SCO2797
2SCC13.05, probable cellobiose transport permease, len: 303 aa; highly similar to TR:Q9X9R5 (EMBL:AJ009797) Streptomyces reticuli permease CebG protein, 275 aa; fasta scores: opt: 1262 z-score: 1477.0 E(): 0; 67.8% identity in 276 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Also contains possible hydrophobic membrane spanning regions.
 
 0.966
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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