STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4299SCD95A.32, possible integral membrane protein, len: 115 aa. Contains possible hydrophobic membrane spanning regions. High content in glycine amino acid residues. (115 aa)    
Predicted Functional Partners:
SCO4298
SCD95A.31, probable carboxylesterase, len: 513 aa; similar to TR:Q9Z545 (EMBL:AL035212) Streptomyces coelicolor putative carboxylesterase SC9B2.14, 502 aa; fasta scores: opt: 1093 z-score: 1041.3 E(): 0; 44.6% identity in 511 aa overlap and to SW:PNBA_BACSU (EMBL:U06089) Bacillus subtilis para-nitrobenzyl esterase (EC 3.1.1.-) PnbA, 489 aa; fasta scores: opt: 823 z-score: 786.2 E(): 0; 38.1% identity in 501 aa overlap. Contains Pfam match to entry PF00135 COesterase, Carboxylesterases and match to Prosite entry PS00122 Carboxylesterases type-B serine active site; Belongs to the type-B [...]
       0.773
SCO4297
SCD95A.30, probable oxidoreduxtase, len: 376 aa; similar to SW:NADO_THEBR (EMBL:X67220) Thermoanaerobacter brockii NADH oxidase, 651 aa; fasta scores: opt: 498 z-score: 552.0 E(): 2.8e-23; 33.6% identity in 354 aa overlap. Contains Pfam match to entry PF00724 oxidored_FMN, FMN oxidoreductase.
       0.661
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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