STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4309Hypothetical protein SCD95A.42; SCD95A.42, unknown, len: 126 aa. (126 aa)    
Predicted Functional Partners:
SCO4310
SCD95A.43, hypothetical protein, len: 98 aa; highly similar to TR:P96070 (EMBL:U09991) Streptomyces violaceus ISP5230 chloramphenicol resistance protein (CMLV) and chloramphenicol phosphotransferase genes, complete CDS (fragment), 89 aa; fasta scores: opt: 450 z-score: 589.5 E(): 2.3e-25; 74.1% identity in 85 aa overlap.
       0.869
SCO4308
SCD95A.41c, possible transcriptional regulator, len: 320 aa; similar to TR:CAB84834 (EMBL:AL162756) Neisseria meningitidis putative transcriptional regulator NMA1605, 282 aa; fasta scores: opt: 476 z-score: 465.7 E(): 1.8e-18; 33.5% identity in 281 aa overlap and to SW:HEXR_ECOLI (EMBL:AE000279) Escherichia coli hex regulon repressor HexR, 289 aa; fasta scores: opt: 337 z-score: 333.6 E(): 4.1e-11; 26.6% identity in 274 aa overlap. Contains Pfam matches to entries PF01418 HTH_6, Helix-turn-helix domain, rpiR family and PF01380 SIS, SIS domain.
       0.789
SCO4307
Conserved hypothetical protein SCD95A.40c; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
       0.721
SCO4306
Hypothetical protein SCD95A.39c; SCD95A.39c, unknown, len: 189 aa.
       0.436
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.