STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4516Hypothetical protein SCD35.23c; SCD35.23c, unknown, len: 119 aa. (119 aa)    
Predicted Functional Partners:
SCO4515
Putative membrane protein; SCD35.22c, hypothetical protein, len: 401 aa; similar to TR:Q9XD98 (EMBL:AF106004) Streptomyces coelicolor hypothetical 27.5 kD protein, 249 aa; fasta scores: opt: 190 z-score: 190.8 E(): 0.0034; 26.8% identity in 190 aa overlap and to TR:Q9F3G6 (EMBL:AL392175) Streptomyces coelicolor putative membrane protein 2SCD4.05, 474 aa; fasta scores: opt: 583 Z-score: 556.4 E(): 2.3e-23; 36.422% identity in 313 aa overlap. Contains possible hydrophobic membrane spanning regions and also possible colied-coil region ar aprox. residues 104..127.
       0.875
SCO4514
SCD35.21c, possible integral membrane protein, len: 192 aa. Contains possible hydrophobic membrane spanning regions.
       0.780
SCO4513
Hypothetical protein SCD35.20c; SCD35.20c, unknown, len: 222 aa.
       0.762
SCO4512
Hypothetical protein SCD35.19c; SCD35.19c, unknown, len: 193 aa.
       0.736
SCO4511
SCD35.18c, possible integral membrane protein, len: 139 aa. Contains possible hydrophobic membrane spanning region.
       0.668
SCO4510
Hypothetical protein SCD35.17; SCD35.17c, unknown, len: 135 aa.
       0.473
SCO4517
SCD35.24c, hypothetical protein, len: 241 aa; C-terminal region similar to TR:Q9KYA0 (EMBL:AL356813) Streptomyces coelicolor conserved hypothetical protein SCK15.04c, 216 aa; fasta scores: opt: 613 Z-score: 714.3 E(): 3.8e-32; 52.792% identity in 197 aa overlap.
       0.416
SCO4518
SCD35.25c, possible integral membrane protein, len: 449 aa. Contains possible hydrophobic membrane spanning regions and possible colied-coil region at aprox. residues 82..110.
       0.416
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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