Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCO4521SCD35.28c, possible secreted protein, len: 361 aa; similar to TR:Q9F3F6 (EMBL:AL392175) Streptomyces coelicolor putative secreted protein 2SCD4.18, 355 aa; fasta scores: opt: 942 Z-score: 1049.8 E(): 7.7e-51; 43.296% identity. Contains possible N-terminal region signal peptide sequence. (361 aa)    
Predicted Functional Partners:
SCO4522
Hypothetical protein SCD35.29c; SCD35.29c, unknown, len: 158 aa.
       0.807
SCO4531
2SCD4.02, possible septum determining protein, len: 145 aa; similar to TR:CAB92601 (EMBL:AL356813) Streptomyces coelicolor putative septum determining protein MinD3, 131 aa; fasta scores: opt: 115 z-score: 155.7 E(): 0.33; 30.7% identity in 137 aa overlap. Contains possible hydrophobic membrane spanning region.
 
     0.781
SCO4530
2SCD4.01, possible membrane protein (fragment), len: >147 aa. Contains possible hydrophobic membrane spanning region; SCD35.37, unknown, len: >77 aa.
 
     0.776
SCO4525
Hypothetical protein SCD35.32; SCD35.32, unknown, len: 293 aa. Contains match to Prosite entry PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
 
     0.759
SCO4527
SCD35.34, possible integral membrane protein, len: 345 aa. Contains possible hydrophobic membrane spanning regions.
 
     0.755
SCO4548
Putative integral membrane protein; SCD16A.35c, partial CDS, unknown, len: >726 aa; 2SCD4.19, possible integral membrane protein (fragment), len: >309 aa. Contains possible hydrophobic membrane spanning regions.
 
     0.723
SCO4528
SCD35.35, possible integral membrane protein, len: 302 aa. Contains possible hydrophobic membrane spanning regions.
 
     0.715
SCP1.173
SCP1.173, possible membrane protein, len: 139aa; contains a possible membrane-spanning hydrophobic region.
 
     0.713
SCO4520
SCD35.27c, hypothetical protein, len: 101 aa; similar to TR:Q9KYA2 (EMBL:AL356813) Streptomyces coelicolor conserved hypothetical protein SCK15.02, 102 aa; fasta scores: opt: 471 Z-score: 568.2 E(): 5.2e-24; 73.684% identity in 95 aa overlap.
       0.709
SCP1.170
SCP1.170, possible integral membrane protein, len: 330aa; similar to TR:Q9L0R7 (EMBL:AL160312) putative integral membrane protein from Streptomyces coelicolor (345 aa) fasta scores; opt: 385, z-score: 452.0, E(): 1e-17, 29.8% identity in 292 aa overlap. Contains possible membrane-spanning hydrophobic regions.
 
     0.700
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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