STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4623Hypothetical protein SCD39.23; SCD39.23, unknown, len: 52 aa. (52 aa)    
Predicted Functional Partners:
SCO4622
SCD39.22c, possible integral membrane protein, len: 166 aa. Contains possible hydrophobic membrane spanning regions.
       0.566
SCO4621
SCD39.21c, traA1, possible sporulation-related protein, len: 179 aa; highly similar to TR:Q54678 (EMBL:U23762) Streptomyces phaeochromogenes involved in intermycelial plasmid transfer TraA, 184 aa; fasta scores: opt: 472 z-score: 523.1 E(): 1.1e-21; 50.0% identity in 172 aa overlap.
       0.532
SCO4620
SCD39.20c, traB1, possible sporulation-related protein, len: 681 aa; highly similar to TR:Q54679 (EMBL:U23762) Streptomyces phaeochromogenes essential for intermycelial plasmid transfer and pock formation, TraB, 678 aa; fasta scores: opt: 1845 z-score: 2002.9 E(): 0; 51.0% identity in 679 aa overlap and middle domain similar to middle domain of SW:SP3E_BACSU (EMBL:M17445) Bacillus subtilis stage III sporulation protein E, SpoIIIE, 787 aa; fasta scores: opt: 208 z-score: 224.4 E(): 4.9e-05; 26.7% identity in 344 aa overlap. Contains Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE [...]
       0.515
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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