STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4694SCD31.19, hypothetical protein, len: 80 aa; similar to part of TR:O54162 (EMBL:AL021411) Streptomyces coelicolor hypothetical 40.9 kD protein SC7H1.03c, 391 aa; fasta scores: opt: 301 z-score: 411.2 E(): 1.8e-15; 58.8% identity in 80 aa overlap. (80 aa)    
Predicted Functional Partners:
SCO4693
SCD31.18, putative membrane protein, len: 86 aa. Contains possible hydrophobic membrane spanning region.
       0.664
SCO4695
SCD31.20, hypothetical protein, len: 181 aa; similar to C-terminal part of many hypothetical proteins, e.g. TR:O54162 (EMBL:AL021411) Streptomyces coelicolor hypothetical 40.9 kD protein SC7H1.03c, 391 aa; fasta scores: opt: 594 z-score: 691.0 E(): 4.7e-31; 53.5% identity in 185 aa overlap.
       0.625
SCO4696
Hypothetical protein SCD31.21; SCD31.21, unknown, len: 155 aa.
       0.547
SCO2817
SCBAC17F8.08c, conserved hypothetical protein, len: 634 aa: similar in regions to many proteins of varying lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein SCM10.16c from Streptomyces coelicolor (714 aa) fasta scores; opt: 1259, Z-score: 1358.4, 43.960% identity (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 (EMBL:AE004874) hypothetical protein from Pseudomonas aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: 1032.5, 36.825% identity (40.250% ungapped) in 611 aa overlap. Contains Pfam match to entry PF00563 EAL, Domain of unknown function and Pfam match to entry PF0 [...]
  
    0.469
SCO4692
SCD31.17, hypothetical protein, len: 215 aa; similar to TR:Q9F3G1 (EMBL:AL392175) Streptomyces coelicolor hypothetical protein 2SCD4.10c, 201 aa; fasta scores: opt: 776 Z-score: 867.6 E(): 1.1e-40; 59.000% identity in 200 aa overlap.
       0.462
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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