STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4810SCD63A.21c, hypothetical protein, len: 342 aa; similar to TR:Q9Z9I2 (EMBL:AB024056) Streptomyces fradiae unknown protein, 306 aa; fasta scores: opt: 645 z-score: 632.8 E(): 8.7e-28; 44.5% identity in 281 aa overlap. (342 aa)    
Predicted Functional Partners:
SCO4811
SCD63A.22, possible integral membrane protein, len: 558 aa. Contains possible hydrophobic membrane spanning regions.
 
     0.862
SCO3324
SCE68.22, hypothetical protein, len: 419 aa; unknown function, probable serine-rich CDS suggested by positional base preference, GC frame analysis and amino acid composition. An alternative start codon is present at codon 4.
 
 
   0.813
SCO2805
2SCC13.13, hypothetical protein, len: 479 aa; similar to SW:SP15_STRGR (EMBL:M32687) Streptomyces griseus sporulation related protein ORF1590, 529 aa; fasta scores: opt: 413 z-score: 469.3 E(): 1.2e-18; 30.4% identity in 326 aa overlap. Contains 2x conserved repeat: YETHD and 3x degenerate repeat: D(T/A)QD(V/L).
  
     0.721
SCO5710
SC9F2.06c, large Pro/Ala/Gly-rich protein of unknown function, len: 1366 aa.
 
     0.696
SCO0736
3SC5B7.14c, possible secreted protein, len: 231 aa. Contains possible N-terminal region cleavable signal peptide sequence.
  
     0.695
SCO4555
SCD16A.28c, possible integral membrane transferase, len: 363aa; similar to TR:Q56803 (EMBL:X78451) O-acetyl transferase from Xanthomonas campestris (364 aa) fasta scores; opt: 123, z-score: 149.6, E(): 0.53, (26.2% identity in 378 aa overlap). Contains possible membrane spanning hydrophobic regions.
 
   
 0.693
SCO3050
Hypothetical protein; SCBAC19G2.05c, unknown, len: 346aa: no significant database matches.
  
     0.648
SCO5307
SC6G9.26c, hypothetical protein, len: 274 aa; unknown function, probable CDS suggested by GC frameplot, positional base preference and amino acid composition. Alternative start codons are present at codons 8 and 14.
 
 
   0.645
SCO5422
SC8F4.26, hypothetical hydrophilic protein, len: 456 aa; contains possible coiled-coil region around residue 250.
  
     0.637
SCO7613
SC2H2.11c, possible integral membrane protein, len: 818 aa. Contains possible hydrophobic membrane spanning regions and 4x degenerate repeat unit: SRTGG.
  
    0.635
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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