STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
SCO5835Putative ATP/GTP-binding protein; SC9B10.02, possible ATP/GTP binding protein, len: 362 aa; similar in N-terminus to other ATP/GTP binding proteins eg. COBW_PSEDE P29937 cobw protein from pseudomonas denitrificans (353 aa), fasta scores; opt: 302 z-score: 390.2 E(): 1.4e-14, 30.1% identity in 366 aa overlap and to TR:Q9RRS7 (EMBL:AE002071) Deinococcus radiodurans CobW protein, putative, DR2408, 320 aa; fasta scores: opt: 434 Z-score: 475.8 E(): 7.2e-19; 34.412% identity in 340 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop). (362 aa)    
Predicted Functional Partners:
SCO5834
SC9B10.01c, putative membrane protein, len: 248 aa. Contains possible hydrophobic membrane spanning region.
       0.788
SCO3430
Putative 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
 
 
 0.741
SCO4715
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.693
SCO3429
SCE9.36, rpmB, probable 50S ribosomal protein L28, len: 73 aa; similar to many e.g. SW:RL28_ECOLI (EMBL:J01677), rpmB, Escherichia coli 50S ribosomal protein L28 (77 aa), fasta scores; opt: 235 z-score: 344.6 E(): 7.1e-12, 47.8% identity in 69 aa overlap. Contains Pfam match to entry PF00830 Ribosomal_L28, Ribosomal L28 family, score 88.70, E-value 1.2e-22; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.602
SCO5564
SC7A1.08c, rpmB, 50S ribosomal protein L28, len: 61aa; similar to many including SW:RL28_BACSU RpmB 50S ribosomal protein L28 from Bacillus subtilis (62 aa) fasta scores; opt: 171, z-score: 301.8, E(): 1.6e-09, (41.0% identity in 61 aa overlap). Contains Pfam match to entry PF00830 Ribosomal_L28, Ribosomal L28 family, score 74.50, E-value 2.2e-18; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.602
SCO0473
SCF76.13c, possible solute-binding lipoprotein, len: 329 aa. Similar to many e.g. Streptococcus parasanguis SW:ADHS_STRPA (EMBL; M26130) adhesin B precursor (saliva-binding protein) (309 aa), fasta scores opt: 354 z-score: 399.1 E(): 7.2e-15 23.7% identity in 317 aa overlap. Contains an appropriately positioned Prosite hit to PS00013 Prokaryotic membrane lipoprotein lipid attachment site, a Pfam match to entry PF01297 Lipoprotein_4, Adhesion lipoprotein and a possible N-terminal signal sequence.
  
  
 0.593
SCO2505
SCC121.08, probable ABC-transporter metal-binding lipoprotein, len: 328 aa; similar to TR:O05703 (EMBL:Z71552) Streptococcus pneumoniae AdcA protein (fragment), 423 aa; fasta scores: opt: 551 z-score: 603.5 E(): 3.2e-26; 39.7% identity in 305 aa overlap and to SW:ZNUA_ECOLI (EMBL:U38702) Escherichia coli, high-affinity zinc uptake system protein ZnuA precursor ZnuA, 328 aa; fasta scores: opt: 294 z-score: 327.0 E(): 8e-11; 26.5% identity in 283 aa overlap. Contains Pfam match to entry PF01297 Lipoprotein_4 and match to Prosite entry PS00013 Prokaryotic membrane lipoprotein lipid attach [...]
  
  
 0.593
SCO2550
Putative lipoprotein; SCC77.17c, possible lipoprotein, len: 171 aa. Contains an appropriately positioned Prosite hit to PS00013 Prokaryotic membrane lipoprotein lipid attachment site and a possible N-terminal signal sequence.
  
  
 0.593
SCO2075
SC4A10.08c, probable DNA-binding protein, len: 239 aa; the N-terminus is Lys- and Ala-rich, containing 13 degenerate AAKK(S)(P/T) repeats and is similar to histone-like proteins e.g. SW:KARP_CHLTR (EMBL:M86605), KarP, Chlamydia trachomatis developmentally regulated gene (207 aa), fasta scores; opt: 245 z-score: 253.5 E(): 8.5e-07, 44.7% identity in 114 aa overlap. This region is also similar to a repeat in TR:O86537 (EMBL:AL031124) S.coelicolor histone-like DNA binding protein (218 aa) (51.4% identity in 72 aa overlap). The C-terminus is similar to SW:DKSA_ECOLI (EMBL:M34945), DskA, Es [...]
  
  
 0.581
SCO6164
Hypothetical protein SC1A9.28c; SC1A9.28c, unknown, len: 192aa; some similarity to TR:O66611 (EMBL:AE000680) putative protein from Aquifex aeolicus (145 aa) fasta scores; opt: 188, z-score: 294.0, E():4.4e-09, (36.6% identity in 93 aa overlap).
  
  
 0.581
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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