STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO5919Hypothetical protein; SC10A5.24c, unknown, len: 134 aa. (134 aa)    
Predicted Functional Partners:
SCO4785
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.735
SCO5918
Hypothetical protein; SC10A5.23c, unknown, len: 103 aa.
       0.661
SCO5920
SC10A5.25c, probable DEAD-box RNA helicase, len: 498 aa; similar to many e.g. RHLE_ECOLI P25888 putative ATP-dependent RNA helicase RhlE (454 aa), fasta scores; opt: 845 z -score: 770.8 E(): 0, 36.2% identity in 434 aa overlap. Con tains possible DEAD-box at aa 221-224 (1 mismatch to prosit e consensus), 2x PS00017 ATP/GTP-binding site motif A (P-lo op) and PS00135 Serine proteases, trypsin family, serine ac tive site, though the last may be spurious. Also contains P fam match to entry helicase_C PF00271, Helicases conserved C-terminal domain, score 108.77 and Pfam match to entry DEA D [...]
       0.656
SCO3330
SCE68.28c, probable acetoin utilization protein, len: 367 aa; similar to proteins known to be required for growth on acetoin and 2,3-butanediol in Bacillus subtilis and Staphylococcus xylosus e.g. SW:ACUC_BACSU (EMBL:L17309), AcuC, Bacillus subtilis acetoin utilization protein (387 aa), fasta scores; opt: 910 z-score: 1032.3 E(): 0, 43.5% identity in 315 aa overlap. Similar to many histone deacetylases e.g. SW:RPD3_YEAST (EMBL:S66438), Rpd3, Saccharomyces cerevisiae histone deacetylases (433 aa) (32.0% identity in 338 aa overlap). Contains Pfam match to entry PF00850 Hist_deacetyl, His [...]
  
    0.464
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.