STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
SCO6007Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. (302 aa)    
Predicted Functional Partners:
SCO6006
Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family.
 
 0.998
SCO6005
Putative lipoprotein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Binds (GlcNAc)2. Can also bind GlcNAc; Belongs to the bacterial solute-binding protein 1 family.
 
 0.997
SCO4240
ABC transporter ATP-binding protein; Part of the ABC transporter complexes DasABC-MsiK and NgcEFG- MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for energy coupling to the transport system.
 
 0.895
SCO0454
SCF51A.32, probable binding-protein dependent transport protein, len: 313 aa. Similar to many including: Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) putative protein SCE134.05C (327 aa), fasta scores opt: 479 z-score: 546.7 E(): 4.3e-23 31.4% identity in 315 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and a Prosite hit to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains multiple possible membrane spanning hydrophobic domains.
 
 
 0.849
SCO0951
SCM11.06c, probable transport system permease protein, len: 310 aa; similar to TR:P73352 (EMBL:D90905) Synechocystis sp. lactose transport system permease protein LacF, 298 aa; fasta scores: opt: 750 z-score: 885.7 E(): 0; 44.9% identity in 292 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and to prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign.
 
 0.847
SCO2433
SCC24.04c, possible sugar transporter membrane protein, len: 313 aa; similar to TR: CAB59596(EMBL:AL132662) Streptomyces coelicolor probable sugar transporter inner membrane protein SCF11.19, 316 aa; fasta scores: opt: 533 z-score: 637.4 E(): 4.5e-28; 36.2% identity in 304 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. Contains also possible hydrophobic membrane spanning regions.
 
 
 0.846
SCO7504
SCBAC17A6.37, possible integral membrane binding-protein-dependent transport protein, len: 316aa; similar to many eg. TR:Q9L0B3 (EMBL:AL163003) putative sugar transporter integral membrane protein from Streptomyces coelicolor (313 aa) fasta scores: opt: 949, Z-score: 1058.2, 48.867% identity (50.671% ungapped) in 309 aa overlap. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component; Prosite match to PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and multiple hydrophobic possible membrane span [...]
 
 0.846
SCO6008
SC7B7.05, probable transcriptional repressor protein, len 403 aa; similar to many eg. XYLR_ANATH Q44406 xylose repressor from Anaerocellum thermophilum (399 aa), fasta scores; opt: 548 z-score: 767.3 E(): 0, 33.1% identity in 393 aa overlap. Contains PS01125 ROK family signature and helix-turn-helix motif at aa positions 29-50 (Score 2016, +6.05 SD).
     
 0.843
SCO0353
SCF41.12, possible binding-protein-dependent transport protein, len: 303 aa. Similar to many including: Streptomyces coelicolor TR:CAB41203 (EMBL; AL049661) putative binding protein dependent transport protein SCE134.05c (327 aa), fasta scores opt: 560 z-score: 661.2 E(): 1.8e-29 35.5% identity in 301 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains multiple potential membrane-spanning hydrophobic domains.
 
 
 0.842
SCO0539
SCF11.19, probable sugar transporter membrane protein, len: 316 aa; similar to TR:CAB52981 (EMBL:AL109950) Streptomyces coelicolor putative integral membrane permease, 319 aa; fasta scores: opt: 606 z-score: 689.2 E(): 5.1e-31; 34.9% identity in 312 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, binding-protein-dependent transport systems inner membrane component and a prosite match to entry PS00402 binding-protein-dependent transport systems inner membrane component signature. Contains probable N-terminal signal sequence.
 
 0.840
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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