STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO6199SC2G5.20, possible secreted esterase, len: 743aa; similar to TR:Q54345 (EMBL:Z50108) esterase, FusH (509 aa) from Streptomyces lividans fasta scores; opt: 619, z-score: 601.5, E(): 3.2e-26,(40.9% identity in 389 aa overlap). Note that the CDS contains Pfam match to entry PF00089 trypsin,Trypsin, score 1.40, E-value 5.6e-05. Also contains possible N-terminal signal sequence. (743 aa)    
Predicted Functional Partners:
SCO6198
SC2G5.19, possible secreted protein, len: 1156aa; alanine rich, similar to TR:O87848 (EMBL:AL031013) hypothetical protein from Streptomyces coelicolor (1147 aa) fasta scores; opt: 2516, z-score: 2119.1, E(): 0, (44.6% identity in 1122 aa overlap). Contains possible N-terminal signal sequence.
 
   
 0.946
SCO6593
Hypothetical protein; SC8A6.14c, unknown, len: 1147 aa; contains two Ala-rich domains, PS00017 ATP/GTP-binding site motif A (P-loop) and probable coiled-coil regions from 238 to 292, 399 to 441, 445 to 488, 490 to 573, 786 to 820, and 829 to 871.
 
   
 0.909
SCP1.201
Hypothetical protein; SCP1.201, unknown, len: 1336aa; similar to TR:O87848 (EMBL:AL031013) hypothetical protein from Streptomyces coelicolor (1147 aa) fasta scores; opt: 1652, z-score: 1478.4, E(): 0, 38.7% identity in 926 aa overlap. Note possible alternative upstream translational start site which would give a possible N-terminal signal sequence. Contains several possible coiled-coil regions.
 
   
 0.797
SCO6591
SC8A6.12c, possible secreted protein, len: 168 aa; c ontains possible N-terminal signal sequence.
     
 0.697
SCO2280
SCC75A.26c, possible TetR-family transcriptional regulator, len: 215 aa. Similar to several other regulators including: Pseudomonas fluorescens TR:AAD31815(EMBL:AF129856) transcriptional regulatory protein PhlF (208 aa), fasta scores opt: 198 z-score: 248.3 E(): 1.9e-06 25.9% identity in 158 aa overlap and Streptomyces coelicolor TR:CAB56137(EMBL:AL117669) putative transcriptional regulator SCF12.11 (206 aa), fasta scores opt: 309 z-score: 381.8 E(): 6.8e-14 30.5% identity in 213 aa overlap. Contains a Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family with th [...]
  
   
 0.686
SCO2282
SCC75A.28c, hypothetical protein, len: 326 aa; similar to TR:Q984U3 (EMBL:AP003012) Rhizobium loti (Mesorhizobium loti) MLL7840 protein 323 aa; fasta scores: opt: 712 Z-score: 794.8 E(): 1.2e-36; 38.365% identity in 318 aa overlap.
    
 
 0.671
SCO6592
SC8A6.13c, probable secreted protein, len: 129 aa; c ontains N-terminal signal sequence and appropriately positi oned PS00013 Prokaryotic membrane lipoprotein lipid attachm ent site.
     
 0.670
SCO6594
SC8A6.15c, probable secreted protein, len: 602 aa; c ontains probable N-terminal signal sequence.
      
 0.669
SCO0545
SCF11.25, possible secreted protein, len: 843 aa; similar to TR:O87849 (EMBL:AL031013) Streptomyces coelicolor putative secreted protein, 602 aa; fasta scores: opt: 2859 z-score: 3026.4 E(): 0; 72.1% identity in 555 aa overlap. Contains possible N-terminal signal sequence.
      
 0.667
SCO6197
SC2G5.18c, possible secreted protein, len: 180 aa; similar to TR:O87846 (EMBL:AL031013) putative secreted protein from Streptomyces coelicolor (168 aa) fasta scores; opt:476, z-score: 556.4, E(): 1e-23, (45.3% identity in 170 aa overlap). Contains possible N-terminal signal sequence.
     
 0.653
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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