SCO6649 protein (Streptomyces coelicolor) - STRING interaction network

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SCO6649

Hypothetical protein SC4G2.23; SC4G2.23, unknown, len: 224 aa. (224 aa)

Predicted Functional Partners:

SCO6648

0.994

SCO6651

0.898

SCO6652

0.898

SCO6650

0.896

SCO6653

0.894

SCO6647

0.891

SCO2495

0.777

SCO6654

0.496

SCO4106

0.461

SCO5892

0.460

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO2495	SCO4106	gene:17760097	gene:17761746	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	0.611
SCO2495	SCO6647	gene:17760097	gene:17764305	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	SC4G2.21c, possible integral membrane protein, len: 264 aa; similar to a hypothetical protein from Rhodobacter sphaeroides TR:O54078 (EMBL:AJ002398) (227 aa), fasta scores; opt: 493 z-score: 616.8 E(): 4.1e-27, 43.6% identity in 220 aa overlap. Also very weak similarity to PGSA_PSEFL (CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase) (195 aa) E:0.0018, 30.8% identity in 146 aa overlap. Contains PS00379 CDP-alcohol phosphatidyltransferases signature.	0.977
SCO2495	SCO6648	gene:17760097	gene:17764306	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	Hypothetical protein SC4G2.22; SC4G2.22, unknown, len: 112 aa.	0.776
SCO2495	SCO6649	gene:17760097	gene:17764307	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	Hypothetical protein SC4G2.23; SC4G2.23, unknown, len: 224 aa.	0.777
SCO2495	SCO6650	gene:17760097	gene:17764308	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	Hypothetical protein SC4G2.24; SC4G2.24, unknown, len: 132 aa.	0.817
SCO2495	SCO6651	gene:17760097	gene:17764309	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	SC5A7.01, possible glycosyl transferase, partial CDS, len: >368 aa; similar to several hypothetical proteins e.g. YV12_MYCTU MTCY20G9.12 (480 aa), fasta sores; opt: 237 z-score: 252.3 E(): 8.1e-07, 29.9% identity in 278 aa overlap, and to WCAL_ECOLI putative colanic acid biosynthesis glycosyl transferase (406 aa), fasta sores; opt: 187 z-score: 194.8 E(): 0.0013, 27.8% identity in 237 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1, score 52.90, E-value 5.5e-14; SC4G2.25, possible glycosyl transferase, partial CDS, len: >78 aa; overlaps a [...]	0.784
SCO2495	SCO6652	gene:17760097	gene:17764310	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	Hypothetical protein SC5A7.02; SC5A7.02, unknown, len: 461 aa; contains 6 degenerate repeats of P(AT)ESAVPA.	0.786
SCO2495	SCO6653	gene:17760097	gene:17764311	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	SC5A7.03, probable integral membrane protein, len: 400 aa. Note 63 aa overlap with convergent downstream ORF. Contains possible hydrophobic membrane spanning regions.	0.827
SCO2495	SCO6654	gene:17760097	gene:17764312	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	Conserved hypothetical protein; SC5A7.04c, unknown, len: 273 aa; some similarity to hypothetical proteins and to Pseudomonas TR:Q52548 (EMBL:D45424) creatinine amidohydrolase (259 aa), fasta sores; opt: 193 z-score: 273.1 E(): 5.6e-08 27.3% identity in 238 aa overlap. Note 63 aa overlap with convergent downstream ORF.	0.473
SCO4106	SCO2495	gene:17761746	gene:17760097	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	Putative membrane protein; SCC82.01, unknownm len: >83 aa; SC7A8.34, possible membrane protein (fragment), len: >541 aa. Contains possible hydrophobic membrane spanning regions.	0.611
SCO4106	SCO5892	gene:17761746	gene:17763552	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	SC3F7.12, redL, probable polyketide synthase, len: 2297 aa; contains 3 modules: N-terminus (start to approx. aa 700) similar to eg. N-terminus of TR:Q50857 (EMBL:U24657) saframycin mx1 synthetase B from Myxococcus xanthus (1770 aa) (fasta scores; E(): 0, 45.0% identity in 691 aa overlap), contains Pfam match to AMP-binding PF00501, AMP-binding enzymes, score 166.66; central module (approx aa 795 to 1800) similar to eg. TR:G2317861 (EMBL:U78289) Streptomyces fradiae tylactone synthase module 3 (1864 aa) (E(): 0, 39.9% identity in 1125 aa overlap), contains PS00606 Beta-ketoacyl synthase [...]	0.506
SCO4106	SCO6647	gene:17761746	gene:17764305	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	SC4G2.21c, possible integral membrane protein, len: 264 aa; similar to a hypothetical protein from Rhodobacter sphaeroides TR:O54078 (EMBL:AJ002398) (227 aa), fasta scores; opt: 493 z-score: 616.8 E(): 4.1e-27, 43.6% identity in 220 aa overlap. Also very weak similarity to PGSA_PSEFL (CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase) (195 aa) E:0.0018, 30.8% identity in 146 aa overlap. Contains PS00379 CDP-alcohol phosphatidyltransferases signature.	0.594
SCO4106	SCO6648	gene:17761746	gene:17764306	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	Hypothetical protein SC4G2.22; SC4G2.22, unknown, len: 112 aa.	0.462
SCO4106	SCO6649	gene:17761746	gene:17764307	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	Hypothetical protein SC4G2.23; SC4G2.23, unknown, len: 224 aa.	0.461
SCO4106	SCO6650	gene:17761746	gene:17764308	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	Hypothetical protein SC4G2.24; SC4G2.24, unknown, len: 132 aa.	0.536
SCO4106	SCO6651	gene:17761746	gene:17764309	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	SC5A7.01, possible glycosyl transferase, partial CDS, len: >368 aa; similar to several hypothetical proteins e.g. YV12_MYCTU MTCY20G9.12 (480 aa), fasta sores; opt: 237 z-score: 252.3 E(): 8.1e-07, 29.9% identity in 278 aa overlap, and to WCAL_ECOLI putative colanic acid biosynthesis glycosyl transferase (406 aa), fasta sores; opt: 187 z-score: 194.8 E(): 0.0013, 27.8% identity in 237 aa overlap. Contains Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1, score 52.90, E-value 5.5e-14; SC4G2.25, possible glycosyl transferase, partial CDS, len: >78 aa; overlaps a [...]	0.485
SCO4106	SCO6652	gene:17761746	gene:17764310	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	Hypothetical protein SC5A7.02; SC5A7.02, unknown, len: 461 aa; contains 6 degenerate repeats of P(AT)ESAVPA.	0.432
SCO4106	SCO6653	gene:17761746	gene:17764311	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	SC5A7.03, probable integral membrane protein, len: 400 aa. Note 63 aa overlap with convergent downstream ORF. Contains possible hydrophobic membrane spanning regions.	0.576
SCO5892	SCO4106	gene:17763552	gene:17761746	SC3F7.12, redL, probable polyketide synthase, len: 2297 aa; contains 3 modules: N-terminus (start to approx. aa 700) similar to eg. N-terminus of TR:Q50857 (EMBL:U24657) saframycin mx1 synthetase B from Myxococcus xanthus (1770 aa) (fasta scores; E(): 0, 45.0% identity in 691 aa overlap), contains Pfam match to AMP-binding PF00501, AMP-binding enzymes, score 166.66; central module (approx aa 795 to 1800) similar to eg. TR:G2317861 (EMBL:U78289) Streptomyces fradiae tylactone synthase module 3 (1864 aa) (E(): 0, 39.9% identity in 1125 aa overlap), contains PS00606 Beta-ketoacyl synthase [...]	SCD17.10, possible bifunctional enzyme deaminase/reductase, len: 376 aa. Similar to both domains of the Escherichia coli bifunctional SW:RIBD_ECOLI (EMBL; X64395) riboflavin biosynthesis protein RibD (367 aa). However the N-terminal domain of SCD17.10 is similar to the E. coli C-terminal reductase domain, fasta scores opt: 209 z-score: 241.1 E(): 4.5e-06 27.0% identity in 222 aa overlap and the C-terminal domain of SCD17.10 is similar to the E. coli N-terminal deaminase domain (blast scores Expect = 3.2e-07, P = 3.2e-07, Identities = 51/192 (26%), Positives = 77/192 (40%)). Also simila [...]	0.506
SCO5892	SCO6648	gene:17763552	gene:17764306	SC3F7.12, redL, probable polyketide synthase, len: 2297 aa; contains 3 modules: N-terminus (start to approx. aa 700) similar to eg. N-terminus of TR:Q50857 (EMBL:U24657) saframycin mx1 synthetase B from Myxococcus xanthus (1770 aa) (fasta scores; E(): 0, 45.0% identity in 691 aa overlap), contains Pfam match to AMP-binding PF00501, AMP-binding enzymes, score 166.66; central module (approx aa 795 to 1800) similar to eg. TR:G2317861 (EMBL:U78289) Streptomyces fradiae tylactone synthase module 3 (1864 aa) (E(): 0, 39.9% identity in 1125 aa overlap), contains PS00606 Beta-ketoacyl synthase [...]	Hypothetical protein SC4G2.22; SC4G2.22, unknown, len: 112 aa.	0.460