STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO7037SC4G1.03, possible secreted protein, len: 1131 aa; similar to TR:CAB88148 (EMBL:AL352956) Streptomyces coelicolor putative transmembrane protein SC1H10.04c, 1433 aa; fasta scores: opt: 1569 z-score: 1600.6 E(): 0; 36.4% identity in 1265 aa overlap. Contains possible cleavable N-terminal signal peptide sequence. (1131 aa)    
Predicted Functional Partners:
SCO6596
SC8A6.17, probable secreted protein, len: 589 aa; co ntains N-terminal signal sequence and PS00213 Lipocalin sig nature.
  
     0.751
SCO7126
Hypothetical protein SC4B10.27; SC4B10.27, unknown, len: 150 aa.
  
     0.671
SCO6595
SC8A6.16, probable secreted protein, len: 380 aa; co ntains N-terminal signal sequence and TTA Leu codon, possib le target for action of bldA.
  
     0.670
SCO6594
SC8A6.15c, probable secreted protein, len: 602 aa; c ontains probable N-terminal signal sequence.
 
     0.649
SCO2503
SCC121.06, probable chitinase precursor, len: 358 aa; similar to C-terminal region of SW:CHID_BACCI (EMBL:D10594) Bacillus circulans chitinase D precursor (EC 3.2.1.14) ChiD, 497 aa; fasta scores: opt: 471 z-score: 502.4 E(): 1.4e-20; 33.0% identity in 370 aa overlap and to SW:CHIX_STROI (EMBL:X71080) Streptomyces olivaceoviridis (Streptomyces corchorusii exochitinase 1 precursor (EC 3.2.1.14) Chi01, 597 aa; fasta scores: opt: 249 z-score: 267.3 E(): 1.7e-07; 31.2% identity in 391 aa overlap. Contains Pfam match to entry PF00704 Glyco_hydro_18 and match to Prosite enry PS01095 Chitinas [...]
 
     0.633
SCO7013
Putative sugar-binding lipoprotein; SC1H10.02C, possible sugar-binding lipoprotein, len: 471 aa. Identical to Streptomyces lividans TR:Q54334(EMBL:U22894) sugar binding lipoprotein precursor, AlgE (471 aa), fasta scores opt: 3154 z-score: 3469.8 E():0 100.0% identity in 471 aa overlap. Contains a possible N-terminal signal sequence and an appropriately positioned Prosite hit to PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
 
     0.609
SCO7233
Putative secreted protein; SC2H12.32, possible secreted protein, len: 934 aa. Note the product of this CDS is rich in the amino acid proline. Contains a possible N-terminal signal sequence. Contains a TTA /leucine codon, possible target for bldA regulation.
  
     0.601
SCP1.274
SCP1.274, possible large secreted protein, len: 2082aa; similar to TR:O86585 (EMBL:AL031514) hypothetical protein SC2H4.02 from Streptomyces coelicolor (2183 aa) fasta scores: E(): 0, 38.4% id in 1958 aa. Contains a possible cleavable N-terminal signal sequence.
 
     0.531
SCO0624
SCF56.08c, possible secreted protein, len: 334 aa. Contains possible N-terminal region signal peptide sequence.
  
     0.529
SCO0505
Putative large, multifunctional secreted protein; SCF6.01, possible multi-domain protein, (fragment), len: >152 aa. Highly similar to Amycolatopsis orientalis TR:CAB45032 (EMBL; AL078635) putative large multi-functional protein (987 aa), fasta scores opt: 595 z-score: 714.7 E(): 1.9e-32 58.6% identity in 152 aa overlap; SCF34.24, possible large, multifunctional secreted protein, partial CDS, len: >891 aa; contains a region of weak similarity to members of the glycosyl hydrolase family at approx. aa 700-890 e.g. to part of SW:CTA2_BACCI (EMBL:D88360), Cit, Bacillus circulans cycloisomal [...]
  
     0.519
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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