STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO7643Hypothetical protein SC10F4.16; SC10F4.16, unknown, len: 91 aa. (91 aa)    
Predicted Functional Partners:
SCO7642
SC10F4.15, conserved hypothetical protein, len: 121 aa; similar to TR:O31535 (EMBL:Z99107) Bacillus subtilis hypothetical protein YetH, 120 aa; fasta scores: opt: 176 z-score: 223.7 E(): 6.3e-05; 29.8% identity in 121 aa overlap.
 
     0.827
SCO7272
SC5H1.20, possible isomerase, len: 127 aa; weakly similar to SW:SDIS_PSEPU (EMBL:L13127), ksI, Pseudomonas putida steroid delta-isomerase (131 aa), fasta scores; opt: 109 z-score: 150.4 E(): 0.47, 26.0% identity in 131 aa overlap.
       0.560
SCO7273
SC5H1.19c, hypothetical protein, len: 136 aa; unknown function, probable CDS suggested by positional base preference, GC frame analysis and amino acid composition. Contains TTA (leucine) codon, possible target for bldA regulation.
       0.560
SCO7641
SC10F4.14, possible dehydrogenase, len: 398 aa; similar to many other Streptomyces coelicolor putative dehydrogenases, e.g. TR:Q9RD04 (EMBL:AL133422) putative dehydrogenase SCM1.40c, 296 aa; fasta scores: opt: 352 z-score: 383.2 E(): 8.2e-14; 33.5% identity in 260 aa overlap.
       0.556
SCO1743
SCI11.32, possible ABC-transporter transmembrane protein, len: 239 aa; weakly similar to putative ABC-transporter protein from S.coelicolor TR:O69995 (EMBL:AL022374) S.coelicolor probable ABC transporter (744 aa), fasta scores; opt: 197 z-score: 224.6 E(): 3.5e-05, 35.4% identity in 212 aa overlap. Contains hydrophobic, possible membrane-spanning regions. May be associated with the adjacent putative ABC-transporter ATP-binding protein.
  
     0.497
SCO0505
Putative large, multifunctional secreted protein; SCF6.01, possible multi-domain protein, (fragment), len: >152 aa. Highly similar to Amycolatopsis orientalis TR:CAB45032 (EMBL; AL078635) putative large multi-functional protein (987 aa), fasta scores opt: 595 z-score: 714.7 E(): 1.9e-32 58.6% identity in 152 aa overlap; SCF34.24, possible large, multifunctional secreted protein, partial CDS, len: >891 aa; contains a region of weak similarity to members of the glycosyl hydrolase family at approx. aa 700-890 e.g. to part of SW:CTA2_BACCI (EMBL:D88360), Cit, Bacillus circulans cycloisomal [...]
  
     0.476
SCO7640
SC10F4.13c, possible lysR-family transcriptional regulator, len: 327 aa; similar to many other Streptomyces coelicolor lysR-family transcriptional regulators, e.g. TR:Q9K3X6 (EMBL:AL359949) putative lysR-family transcriptional regulator 2SCG61.40c, 303 aa; fasta scores: opt: 376 z-score: 418.1 E(): 9.5e-16; 34.0% identity in 318 aa overlap. Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and possible helix-turn-helix motif at residues 16..37 (+5.92 SD).
       0.405
SCO0069
Hypothetical protein; SCJ4.50, unknown, len: 1052 aa.
  
     0.400
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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