STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCP1.02cHypothetical protein; SCP1.02c, unknown, len: 401aa. (401 aa)    
Predicted Functional Partners:
SCO6025
Hypothetical protein; SC1C3.13, unknown, len: 655 aa; C-terminus is similar to upstream genes TR:O69849 (EMBL:AL023702) SC1C3.07 (opt: 399 Z-score: 441.0 E(): 6.2e-17; 31.751% identity in 337 aa overlap) and TR:O69848 (EMBL:AL023702) SC1C3.06 (opt: 428 Z-score: 473.3 E(): 9.9e-19; 32.022% identity in 356 aa overlap).
  
     0.579
SCP1.01c
Hypothetical protein; SCP1.01c, unknown, len: 207aa.
       0.550
SCP1.03c
Hypothetical protein; SCP1.03c, unknown, len: 72aa.
       0.541
SCP1.04c
Hypothetical protein; SCP1.04c, unknown, len: 78aa.
       0.541
SCO5278
Putative magnesium chelatase; SCCB12.02, possible ion chelatase, len: 655 aa; similar to TR: SW:CHLD_SYNP7 (EMBL:AB003135) Synechococcus sp. magnesium-chelatase subunit ChlD (MG-protoporphyrin IX chelatase) ChlD, 677 aa; fasta scores: opt: 304 z-score: 269.4 E(): 1.5e-07; 26.6% identity in 688 aa overlap.
  
     0.534
SCO4224
Hypothetical protein; 2SCD46.38c, unknown, len: 421aa.
  
     0.505
SCO3010
SCE33.12c, hypothetical protein, len: 315 aa; similar to TR:O05887 (EMBL:Z95121) hypothetical 22.5 kD protein MTCY20B11.17c, 213 aa; fasta scores: opt: 189 z-score: 191.8 E(): 0.0032; 36.8% identity in 228 aa overlap.
   
    0.497
SCO1514
Adenine phosphoribosiltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.468
SCO7248
Hypothetical protein SC7A12.15; SC7A12.15, unknown, len: 206 aa. Weakly similar to several proteins of undefined function e.g. Streptomyces coelicolor TR:CAB72201(EMBL:AL138851) SCE59.14C (196 aa), fasta scores opt: 209 z-score: 240.8 E(): 6.1e-06 33.7% identity in 193 aa overlap.
  
     0.468
SCO1950
Hypothetical protein; Involved in cell division and chromosome segregation (By similarity). Involved in sporulation. May coordinate the cessation of aerial hyphae growth and subsequent chromosome segregation and/or septation. Required for expression of the ParB partioning protein during sporogenesis. Activates its own transcription and represses WhiB. Binds with low affinity to its own promoter and to the Parp2 sporulation-specific promoter. Also binds directly to the RNA polymerase sigma factor WhiG, leading to inhibition of WhiG-dependent transcription in a dose-dependent manner ; Be [...]
   
    0.442
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.