STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCP1.90cSCP1.90c, possible ATP/GTP-binding protein, len: 228aa; contains Prosite match to PS00017 ATP/GTP-binding site motif A (P-loop). (228 aa)    
Predicted Functional Partners:
SCP1.91c
SCP1.91c, possible GntR-family transcriptional regulator, len: 252aa; similar to many from extrachromosomal genetic elements eg. TR:Q9RIQ2 (EMBL:AJ243257) KorA protein from plasmid pSNA1 of Streptomyces natalensis (245 aa) fasta scores; opt: 477, z-score: 554.9, E(): 1.9e-23, 37.9% identity in 243 aa overlap and SW:P22405 (KORA_STRLI) KorA protein from plasmid pIJ101 of Streptomyces lividans (241 aa) fasta scores; opt: 393, z-score: 459.0, E(): 4.3e-18, 34.9% identity in 235 aa overlap. Contains Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family and helix-turn [...]
       0.875
SCO4288
Putative phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.519
SCP1.88c
SCP1.88c, possible hydrolase, len: 193aa; weakly similar to many eg. TR:Q9X8G0 (EMBL:AL049819) putative hydrolase from Streptomyces coelicolor (193 aa) fasta scores; opt: 177, z-score: 224.6, E(): 4.8e-05, 30.7% identity in 153 aa overlap and SW:O07900 (VIBB_VIBCH) vibriobactin-specific isochorismatase (EC 3.3.2.1) (293 aa) fasta scores; opt: 163, z-score: 205.0, E(): 0.0006, 23.9% identity in 180 aa overlap. Contains Pfam match to entry PF00857 Isochorismatase, Isochorismatase family.
       0.453
SCO7255
SC5H1.37, hypothetical protein, len: 364 aa; unknown function, similar to TR:P73120 (EMBL:D90903) Synechocystis sp. hypothetical protein (358 aa), fasta scores; opt: 492 z-score: 559.6 E(): 7.6e-24, 31.6% identity in 364 aa overlap.
   
    0.443
SCP1.87c
SCP1.87c, possible oxidoreductase, len: 303aa; weakly similar to many eg. TR:O54079 (EMBL:AJ223781) thioredoxin reductase (EC 1.6.4.5) from Staphylococcus aureus (311 aa) fasta scores; opt: 250, z-score: 285.3, E(): 2e-08, 27.3% identity in 311 aa overlap.
       0.441
SCP1.89c
Hypothetical protein; SCP1.89c, unknown, len: 389aa.
       0.441
SCO0373
SCF41.32c, possible secreted protein, len: 199 aa. Contains a possible N-terminal signal sequence.
   
    0.416
SCO2678
SC6D10.21, hypothetical protein, len: 171 aa; similar to TR:CAB55735 (EMBL:AL117387) Streptomyces coelicolor putative secreted protein SCF41.32c, fasta scores: opt: 399 z-score: 488.3 E(): 8.7e-20; 45.6% identity in 169 aa overlap.
   
    0.416
SCO7304
Conserved hypothetical protein SC5F8.14; SC5F8.14, unknown, len: 557 aa. Highly similar to several proteins of undefined function including: Mycobacterium tuberculosis TR:P71838(EMBL:Z80226) (566 aa), fasta scores opt: 2386 z-score: 2598.2 E():0 63.1% identity in 553 aa overlap and Deinococcus radiodurans TR:Q9RYS0(EMBL:AE001863) (554 aa), fasta scores opt: 2249 z-score: 2449.3 E():0 60.2% identity in 555 aa overlap.
  
     0.409
SCO2654
SC8E4A.24, hypothetical protein, len: 194 aa; similar to various hypothetical proteins, e.g. TR:CAB56360 (EMBL:AL118514) Streptomyces coelicolor hypothetical 21.6 kD protein SCD25.16c, 194 aa; fasta scores: opt: 700 z-score: 857.1 E(): 0; 58.5% identity in 188 aa overlap.
  
     0.407
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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