STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCP1.296SCP1.57c; SCP1.296, unknown, len: 179aa. (179 aa)    
Predicted Functional Partners:
SCP1.295
SCP1.295, possible regulatory protein, len: 147aa; similar to others from Streptomyces coelicolor eg. TR:Q53897 (EMBL:X60316) AbaA pleiotropic regulatory protein from Streptomyces coelicolor (192 aa) fasta scores; opt: 112, z-score: 149.1, E(): 0.77, 31.7% identity in 120 aa overlap. Contains TTA encoded leucine at residue 11, possible target for bldA regulation.
       0.773
SCP1.294
Hypothetical protein; SCP1.294, unknown, len: 145aa; similar to regions of others of undefined function eg. TR:Q9ZBJ0 (EMBL:AL035161) conserved hypothetical protein from Streptomyces coelicolor (860 aa) fasta scores; opt: 272, z-score: 347.5, E(): 6.9e-12, 39.4% identity in 127 aa overlap.
       0.723
sapC-2
SCP1.297, spore associated protein, SapC, len: 150aa; similar to TR:Q9KYK7 (EMBL:AL356593) putative secreted protein from Streptomyces coelicolor (155 aa) fasta scores; opt: 346, z-score: 450.7, E(): 1.2e-17, 40.5% identity in 131 aa overlap. Contains a possible cleavable N-terminal signal sequence.
       0.675
SCP1.299
SCP1.298, probable hydratase, len: 274aa; similar to many eg. SW:P77608 (MHPD_ECOLI) 2-keto-4-pentenoate hydratase (EC 4.2.1.-) from Escherichia coli (269 aa) fasta scores; opt: 420, z-score: 525.4, E(): 8.5e-22, 34.3% identity in 245 aa overlap. Contains Pfam match to entry PF01689 Hyratase_decarb, Hydratase/decarboxylase.
       0.675
SCP1.300
SCP1.300, possible acetaldehyde dehydrogenase (acylating), len: 293aa; similar to many eg. TR:Q51962 (EMBL:U13232) acetaldehyde dehydrogenase (acylating) from Pseudomonas putida (307 aa) fasta scores; opt: 550, z-score: 658.2, E(): 3.4e-29, 35.0% identity in 294 aa overlap.
       0.600
SCP1.301
SCP1.301, possible 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-), len: 338aa; part of the 3-hydroxyphenylpropionate degradation pathway, strongly similar to many eg. SW:P51020 (MHPE_ECOLI) 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) from Escherichia coli (337 aa) fasta scores; opt: 865, z-score: 959.9, E(): 0, 41.8% identity in 328 aa overlap and TR:Q9X9Q0 (EMBL:Y18574) Nikb protein from Streptomyces tendae (357 aa) fasta scores; opt: 1441, z-score: 1593.4, E(): 0, 67.4% identity in 319 aa overlap. Contains Pfam match to entry PF00682 HMGL-like, HMGL-like.
       0.600
SCP1.302
SCP1.302, possible lysase, len: 287aa; similar to many eg. SW:P17725 (CILB_KLEPN) citrate lyase beta chain (EC 4.1.3.6) (289 aa) fasta scores; opt: 392, z-score: 446.6, E(): 2.1e-17, 31.5% identity in 286 aa overlap.
       0.600
sapE-2
SCP1.303, spore associated protein, SapE, len: 174aa; similar to many of undefined function eg. TR:Q9ZC37 (EMBL:AL031866) hypothetical protein from Yersinia pestis (180 aa) fasta scores; opt: 490, z-score: 646.6, E(): 1.5e-28, 47.8% identity in 157 aa overlap. Contains Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain.
       0.600
sapD-2
SCP1.304, spore associated protein, SapD, len: 296aa.
       0.567
SCP1.292c
SCP1.292c, possible regulatory protein, len: 74aa; similar to many eg. TR:Q53896 (EMBL:X60316) AbaA pleiotropic regulatory protein from Streptomyces coelicolor (192 aa) fasta scores; opt: 149, z-score: 226.2, E(): 3.9e-05, 40.4% identity in 57 aa overlap and TR:Q9RHR6 (EMBL:AB025200) ORF76 protein from plasmid pNO33 of Streptomyces albulus (76 aa) fasta scores; opt: 309, z-score: 448.7, E(): 1.6e-17, 60.3% identity in 73 aa overlap.
       0.425
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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