STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCP1.350Hypothetical protein; SCP1.350, unknown, len: 78aa. (78 aa)    
Predicted Functional Partners:
SCP1.351
Hypothetical protein; SCP1.351, unknown, len: 72aa.
       0.773
SCO3029
Putative L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.702
SCP1.349
Hypothetical protein; SCP1.349, unknown, len: 131aa.
       0.556
SCO4367
SCD19.22, possible oxidoreductase, len: 951 aa; N-terminal domain similar to SW:GLCD_ECOLI (EMBL:L43490) Escherichia coli glycolate oxidase subunit GlcD, 499 aa; fasta scores: opt: 351 z-score: 387.8 E(): 4.3e-14; 31.2% identity in 497 aa overlap and C-terminal domain similar to SW:GLCF_ECOLI (EMBL:L43490) Escherichia coli glycolate oxidase iron-sulfur subunit GlcF, 407 aa; blastp scores: Score= 113 (39.8 bits), Expect= 8.0e-10, Sum P(2)= 8.0e-10; Identities= 26/78 (33%), Positives= 39/78 (50%) and Identities= 61/237 (25%), Positives= 91/237 (38%). Contains Pfam match to entry PF01565 [...]
  
 0.552
SCO5966
SCBAC16H6.01c, possible oxidase, len: >1032aa: similar to many of undefined function eg. TR:Q9EZK2 (EMBL:AF289509) putative oxidase YdiJ-like protein from Pseudomonas putida (1006 aa) fasta scores; opt: 880, Z-score: 889.5, 27.930% identity (31.672% ungapped) in 1024 aa overlap and TR:Q9F2Y0 (EMBL:AL392149) putative oxidoreductase SCD19.22 from Streptomyces coelicolor (951 aa) fasta scores; opt: 622, Z-score: 628.7, 49.698% identity (53.813% ungapped) in 994 aa overlap. Contains Prosite match to PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature; Pfam match to entry PF029 [...]
  
 0.552
SCO7572
SC5F1.26, possible oxidoreductase, len: 998 aa; similar to TR:Q9KKW5 (EMBL:AE004425) Vibrio cholerae oxidoreductase/iron-sulfur cluster-binding protein VCA0985, 959 aa; fasta scores: opt: 1999 z-score: 2189.0 E(): 0; 35.3% identity in 966 aa overlap. Contains Pfam matches to entries PF01565 FAD_binding_4, FAD binding domain and PF00037 fer4, 4Fe-4S binding domain and matches to Prosite entries PS00422 Granins signature 1 and PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
  
 0.552
SCP1.352
Hypothetical protein; SCP1.352, unknown, len: 401aa.
       0.538
SCO5425
Phosphate acetyltransferase (fragment); Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.405
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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