STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcho1FCH domain only protein 1; Belongs to the adaptor complexes medium subunit family. (233 aa)    
Predicted Functional Partners:
Itsn2
Intersectin-2.
   
 0.995
Itsn1
Intersectin-1.
   
 0.990
Eps15
Epidermal growth factor receptor substrate 15.
    
 0.893
Ap2a2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.879
Pacsin3
Protein kinase C and casein kinase II substrate protein 3.
   
 
 0.832
Ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.827
Ap2m1
AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 0.822
Ap2b1
AP-2 complex subunit beta.
    
 0.778
Srgap1
SLIT-ROBO Rho GTPase-activating protein 1.
   
 0.777
Srgap2
SLIT-ROBO Rho GTPase-activating protein 2.
   
 0.775
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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