STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I79_006232PAX-interacting protein 1. (79 aa)    
Predicted Functional Partners:
Paxip1
PAX-interacting protein 1.
 
  
  0.933
Tp53bp1
Tumor suppressor p53-binding protein 1.
    
 0.902
I79_006022
Histone demethylase UTY.
   
 0.865
Rbbp5
Retinoblastoma-binding protein 5.
   
 0.840
Ash2l
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.838
Topbp1
DNA topoisomerase II-binding protein 1.
   
 
 0.836
I79_012607
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.807
Pagr1
PAXIP1-associated protein 1.
    
 0.802
I79_002734
Lysine-specific demethylase 6B.
   
 0.788
Wdr5
WD repeat-containing protein 5.
   
 0.788
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.