STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kcnj10ATP-sensitive inward rectifier potassium channel 10. (379 aa)    
Predicted Functional Partners:
Kcnj16
Inward rectifier potassium channel 16.
  
0.888
Aqp4
Aquaporin-4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.690
Kcnq1
Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.
   
  
 0.669
Trpv5
Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.646
Gjb3
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.637
Kcnh1
Potassium voltage-gated channel subfamily H member 1.
      
 0.605
Ndufs4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial.
      
 0.597
I79_018112
Lysosomal-trafficking regulator.
      
 0.597
Cav1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
 
 0.574
Kcnj4
Inward rectifier potassium channel 4.
  
0.531
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (20%) [HD]