STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I79_009291Beta-secretase 2; Belongs to the peptidase A1 family. (378 aa)    
Predicted Functional Partners:
Fyn
Proto-oncogene tyrosine-protein kinase Fyn.
   
 
 0.807
App
Amyloid beta A4 protein.
    
 0.779
Txndc5
Thioredoxin domain-containing protein 5; Belongs to the protein disulfide isomerase family.
    
 
 0.619
Tmem200a
Transmembrane protein 200A.
      
 0.565
Gga1
ADP-ribosylation factor-binding protein GGA1.
    
 0.556
I79_022876
ADP-ribosylation factor-binding protein GGA2.
    
 0.549
I79_023780
ADP-ribosylation factor-binding protein GGA2.
    
 0.549
I79_001115
Amyloid-like protein 2.
    
 0.543
I79_012792
Amyloid-like protein 1.
    
 0.531
I79_003190
VWFA and cache domain-containing protein 1.
      
 0.483
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.