STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Psme3Proteasome activator complex subunit 3. (254 aa)    
Predicted Functional Partners:
Ifng
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
 
 0.919
Tnf
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 
 0.917
Psme1
Proteasome activator complex subunit 1.
    
0.914
Psme2
Proteasome activator complex subunit 2.
  
 
 
0.911
Nr1h3
Oxysterols receptor LXR-alpha.
   
  0.903
Rxra
Retinoic acid receptor RXR-alpha.
   
  0.903
Psma7
Proteasome endopeptidase complex.
   
 0.901
Psmb7
Proteasome subunit beta.
   
 0.837
Psmd14
26S proteasome non-ATPase regulatory subunit 14.
   
 0.821
Psmd6
26S proteasome non-ATPase regulatory subunit 6.
   
 0.782
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.