Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DHFR | Fpgs | Q2MH30 | G3HV07 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.998 |
| DHFR | I79_001722 | Q2MH30 | G3GVI3 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.973 |
| DHFR | I79_006465 | Q2MH30 | G3H7X0 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Glycine dehydrogenase [decarboxylating], mitochondrial. | 0.964 |
| DHFR | I79_015041 | Q2MH30 | G3HVQ1 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Thymidylate synthase. | 0.999 |
| DHFR | ITPA | Q2MH30 | G3H436 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.487 |
| DHFR | Rrm1 | Q2MH30 | G3I3B7 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.610 |
| DHFR | Shmt2 | Q2MH30 | G3HW36 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.997 |
| DHFR | Slc25a42 | Q2MH30 | G3H477 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.702 |
| DHFR | Tk1 | Q2MH30 | G3H3F8 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Thymidine kinase. | 0.911 |
| Fpgs | DHFR | G3HV07 | Q2MH30 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.998 |
| Fpgs | I79_001722 | G3HV07 | G3GVI3 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.949 |
| Fpgs | I79_006465 | G3HV07 | G3H7X0 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Glycine dehydrogenase [decarboxylating], mitochondrial. | 0.661 |
| Fpgs | I79_015041 | G3HV07 | G3HVQ1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthase. | 0.960 |
| Fpgs | ITPA | G3HV07 | G3H436 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.540 |
| Fpgs | Shmt2 | G3HV07 | G3HW36 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.950 |
| Fpgs | Slc25a42 | G3HV07 | G3H477 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.493 |
| Fpgs | Tk1 | G3HV07 | G3H3F8 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidine kinase. | 0.531 |
| I79_001722 | DHFR | G3GVI3 | Q2MH30 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.973 |
| I79_001722 | Fpgs | G3GVI3 | G3HV07 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.949 |
| I79_001722 | I79_006465 | G3GVI3 | G3H7X0 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Glycine dehydrogenase [decarboxylating], mitochondrial. | 0.982 |
page 1 of 4