STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TecTyrosine-protein kinase. (500 aa)    
Predicted Functional Partners:
Blnk
B-cell linker protein.
   
 0.927
Plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.925
Plcg1
Phosphoinositide phospholipase C.
    
 0.925
Vav2
Guanine nucleotide exchange factor VAV2.
   
 0.925
Lcp2
Lymphocyte cytosolic protein 2.
   
 0.913
Epor
Erythropoietin receptor.
    
 0.689
Socs1
Suppressor of cytokine signaling 1.
   
 0.673
Socs3
Suppressor of cytokine signaling 3.
   
 0.665
I79_025584
Interleukin-2 receptor subunit beta.
   
 0.631
Stat6
Signal transducer and activator of transcription.
   
 0.607
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.