STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I79_023818Dedicator of cytokinesis protein 8; Belongs to the DOCK family. (1309 aa)    
Predicted Functional Partners:
Cdc42
Cell division control protein 42-like.
   
 0.881
Rhoj
Rho-related GTP-binding protein RhoJ.
   
 0.613
Lrch1
Leucine-rich repeat and calponin-likey domain-containing protein 1.
   
 
 0.600
Rhoq
Rho-related GTP-binding protein RhoQ.
   
 0.571
Arid4b
AT-rich interactive domain-containing protein 4B.
      
 0.553
Kank2
Dedicator of cytokinesis protein 7; Belongs to the DOCK family.
  
 
 
0.552
Rac1
Ras-related C3 botulinum toxin substrate 1.
   
 0.525
Rac3
Ras-related C3 botulinum toxin substrate 3.
   
 0.525
I79_022271
Ras-related C3 botulinum toxin substrate 2.
   
 0.525
I79_012275
Wiskott-Aldrich syndrome protein-like.
   
  
 0.508
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.