STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Txn2Thioredoxin, mitochondrial. (64 aa)    
Predicted Functional Partners:
Txnip
Thioredoxin-interacting protein.
    
 0.974
Prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.950
Prdx3
Thioredoxin-dependent peroxide reductase, mitochondrial.
  
 0.926
Msra
Peptide methionine sulfoxide reductase.
   
 0.905
Prdx1
Peroxiredoxin-1.
  
 0.853
Txnrd2
Thioredoxin reductase 2, mitochondrial.
  
 0.852
Mrpl11
39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
   
   0.810
Polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.807
I79_022036
Peroxiredoxin-2.
  
 0.799
Prdx2
Peroxiredoxin-2.
  
 0.797
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.