STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE70956.1hydroxymethylglutaryl-CoA lyase. (289 aa)    
Predicted Functional Partners:
SFF02881.1
methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.961
SFE67997.1
3-oxoacid CoA-transferase subunit B.
  
 
 0.906
SFF18558.1
Acetyl-CoA carboxylase, carboxyltransferase component.
 0.850
SFF36362.1
3-hydroxyacyl-CoA dehydrogenase.
 
 
 0.844
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.835
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.835
SFF06015.1
Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component.
   
 
 0.782
SFF35132.1
2-oxoisovalerate dehydrogenase E1 component.
   
 
 0.782
SFE44036.1
Allosteric NADP-dependent malic enzyme.
   
 
 0.773
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.772
Your Current Organism:
Thermoflexibacter ruber
NCBI taxonomy Id: 1003
Other names: ATCC 23103, DSM 9560, Flexibacter ruber, IFO 16677, LMG 13857, LMG:13857, NBRC 16677, T. ruber, strain GEY
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