STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFF47769.1Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain. (77 aa)    
Predicted Functional Partners:
SFE88856.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
   
 
 0.660
SFF50291.1
Cysteine desulfurase.
  
 
 0.649
SFF47755.1
Glucose/arabinose dehydrogenase, beta-propeller fold.
       0.596
nuoB
NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
    0.576
SFE41333.1
Iron-sulfur cluster assembly protein; Belongs to the HesB/IscA family.
  
 
 0.556
SFF32993.1
Iron-binding apoprotein IscA; Belongs to the HesB/IscA family.
  
 
 0.556
SFF15703.1
4Fe-4S dicluster domain-containing protein.
   
    0.487
SFF30157.1
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase subunit (chain I).
   
    0.487
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
   0.441
SFE92035.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
   0.441
Your Current Organism:
Thermoflexibacter ruber
NCBI taxonomy Id: 1003
Other names: ATCC 23103, DSM 9560, Flexibacter ruber, IFO 16677, LMG 13857, LMG:13857, NBRC 16677, T. ruber, strain GEY
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.